Developing sensors to detect diseases early
Official title: Ratiometric Metabolite Sensors for the Early Detection of Disease
Funded at Montana State University - Bozeman · NIH-11021356 · Data updated 2026-11-12
This study is working on new colorful dyes and proteins that can help doctors spot signs of diseases like Alzheimer's more quickly, so they can diagnose and manage patients better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Montana State University - Bozeman NIH-funded |
| Lab location | 1 site (Bozeman, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $316,668 |
| NIH project number | 1R35GM157218-01 |
| Project ID | NIH-11021356 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for or diagnosed with Alzheimer's disease or related dementias.
✕Less likely to help
Patients with conditions unrelated to metabolic changes or those not at risk for Alzheimer's disease may not benefit from this research.
What this research studies
This research focuses on creating innovative fluorescent dyes and proteins that can help detect disease-related metabolites in real-time. By using advanced imaging techniques, the team aims to improve the understanding of various diseases, particularly Alzheimer's disease, through the development of novel biosensors. The project involves synthesizing new fluorescent compounds and studying specific proteins associated with disease processes, which could lead to earlier diagnosis and better patient management.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of diseases like Alzheimer's, improving treatment outcomes for patients.
How similar studies have gone: Other research has shown promise in using fluorescent sensors for disease detection, indicating that this approach could be effective.
Where this research is happening
-
Montana State University - Bozeman
Bozeman, United States Active
Researchers
- Principal investigator: Lemon, Christopher Michael — Montana State University - Bozeman
- Study coordinator: Lemon, Christopher Michael
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.