Sponsor or institution
Clinical trials and research at Coriell Institute for Medical Research
As of November 12, 2026, Find a Trial lists 33 NIH-funded research projects at this institution, with $22.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 33NIH research projects
NIH-funded research (33)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Mysterious DNA marks in sperm and eggs: how sex shapes germline methylation
This grant looks at how DNA methylation patterns in sperm and eggs become different between the sexes and why that matters for fertility and healthy offspring.
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NIGMS Human Genetic Cell Repository Support
A national biobank helps scientists by keeping high-quality human cell lines and DNA from people with genetic differences and healthy individuals for research and teaching.
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Centralized bank of human cell lines and DNA for biomedical research
A national repository funded by NIH provides high-quality human cell lines and DNA from people with inherited disorders and diverse backgrounds to researchers.
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Human Genetic Cell Repository for Biomedical Research
A national resource center will keep and expand a library of well-documented human cell lines and DNA from people with inherited disorders and diverse backgrounds to help researchers study genetic diseases.
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NIGMS Human Genetic Cell Repository for Biomedical Research
This NIH grant supports Coriell to maintain and expand a centralized collection of human cell lines and DNA from people with inherited disorders and diverse backgrounds to speed biomedical discoveries.
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NHGRI Sample Repository for Human Genetic Research
A national resource is renewed to provide a large, publicly accessible collection of human biospecimens and genomic data to support trustworthy genetic research.
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NRF2-ACSS2 Axis in Alcohol-Linked Esophageal Health
This grant studies how a cellular power switch (NRF2-ACSS2) drives alcohol-related changes in esophageal cells and tissue, with findings that could guide future prevention.
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A center for managing human genetic samples and data related to neurological disorders.
This study is all about gathering and sharing biological samples and their related genetic information to help researchers better understand neurological conditions, which could lead to better treatments for patients like you.
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Boost umbilical cord blood stem cells with PPAR‑alpha medicines
This project uses PPAR‑alpha activating drugs to grow more blood‑forming stem cells from stored umbilical cord blood to help people who need stem cell transplants.
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Targeting YAP1 to stop stomach cancer spread and immune suppression
This project looks for ways to block a protein called YAP1 to help people with advanced stomach (gastric) cancer that has spread to the lining of the abdomen.
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Alcohol-related changes in the esophagus involving NRF2 and ACSS2
This project looks at whether blocking two proteins called NRF2 and ACSS2 can stop alcohol-related damage to the esophagus that affects people who drink alcohol.
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Making PARP Inhibitors Work for More Breast and Ovarian Cancers
This research explores how combining two types of medicines might help PARP inhibitors treat more people with breast and ovarian cancer, even if they don't have a specific genetic mutation.
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Improving Solid Tumor Treatment with Combined Epigenetic Therapies
This project looks at how combining two specific types of drugs can help improve the effectiveness of immunotherapy for patients with solid tumors.
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Targeting CDKs for Cancer Treatment
This project explores new ways to reprogram cancer cells, particularly in breast cancer and myeloid leukemias, by targeting specific proteins called CDKs to change how genes are expressed.
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Managing Patient Samples for Cancer Research
This core facility helps collect and manage patient blood, bone marrow, and tissue samples to support important cancer research projects.
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New Ways to Use Epigenetic Therapies for Cancer
This project explores new ways to use epigenetic therapies to help patients with breast cancer and other cancers.
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Central public collection of human DNA and cell samples
A public resource that stores and shares DNA, cell lines, and other biospecimens from diverse people to help researchers studying human genetics.
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National collection of human cell lines and DNA for genetic research
This project maintains and grows a national collection of human cell lines and DNA to help researchers studying inherited conditions and human genetic variation.
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Understanding how acute myeloid leukemia resists targeted therapies
This study is looking at why some patients with acute myeloid leukemia (AML) stop responding to certain cancer treatments, and it aims to find new ways to help those patients by understanding the genes involved in this resistance.
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Understanding and treating a specific type of esophageal cancer with high NRF2 levels
This study is looking at a specific type of esophageal cancer that has high levels of a protein called NRF2, which might help the cancer grow, and the researchers want to find ways to block this protein to create better treatments for patients.
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Investigating how a specific pathway affects blood stem cell function
This study is looking at how a specific pathway in our cells can help improve the health and function of blood stem cells, which are important for making blood, with the hope of finding better treatments for blood disorders like leukemia.
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Increasing the number of blood stem cells from umbilical cord blood
This study is looking at ways to increase the number of important blood stem cells from umbilical cord blood to make them more available for transplants, which can help people with blood-related illnesses.
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Understanding and targeting cancer stemness and immune suppression in advanced gastric cancer
This study is looking at how a protein called YAP1 affects advanced stomach cancer, especially in patients with cancer that has spread to the lining of the abdomen, to find new ways to treat this tough condition and help improve outcomes for patients.
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Investigating how alcohol affects metabolism and esophageal health
This study is looking at how drinking alcohol affects metabolism and esophageal health, and it's for anyone interested in understanding the risks of alcohol on the esophagus, as researchers test ways to prevent these issues.
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Training program for future cancer researchers
The Career Enhancement Program is designed to help new scientists and doctors who want to study how genes affect cancer, by giving them training and support in important areas like cancer biology and drug development.
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Funding innovative projects for cancer epigenetic therapies
This study is looking for new ways to treat cancer by exploring how changes in our genes can affect the disease, and it's designed to help scientists work together to find better therapies that could benefit patients like you.
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Exploring new treatments for breast and ovarian cancer using epigenetic therapy and PARP inhibitors
This study is looking at how a new combination of cancer treatments might work better for people with breast and ovarian cancer, even if they don't have a specific gene mutation, by boosting the body's immune response to help the therapy be more effective.
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Combining drugs to improve cancer treatment by reversing DNA changes
This study is looking at a new way to treat solid tumors by using special drugs that change how DNA works in cancer cells, which might make other treatments, like immunotherapy, work better for patients.
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Targeting specific proteins to improve cancer treatment
This study is looking for new ways to help treat myeloid leukemias by finding drugs that can change how cancer cells behave, making them more responsive to current treatments and possibly helping the immune system fight the cancer better.
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Collecting and analyzing patient samples to improve treatments for blood cancers
This study is looking for patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) to share blood and bone marrow samples during their treatment, so researchers can learn more about how to make treatments better and help patients feel better in the future.
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Exploring the role of specific genes in cancer treatment
This study is looking at how specific genes, like CDK4 and CDK9, can be used to improve cancer treatments, and it’s for patients who want to explore new ways to make their current therapies work better.
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Support for cancer epigenetic therapy research
This study is all about helping researchers work together better to improve cancer treatments, which means patients could see better clinical trials and therapies in the future.
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New treatments targeting gene expression changes in cancer
This study is looking at new treatments for cancer that change how genes work, especially for patients with breast cancer, to help make current therapies more effective and tackle any resistance to them.
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