NIGMS Human Genetic Cell Repository Support
Official title: Resource Core
Funded at Coriell Institute for Medical Research · NIH-11414866 · Data updated 2026-11-12
A national biobank helps scientists by keeping high-quality human cell lines and DNA from people with genetic differences and healthy individuals for research and teaching.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Coriell Institute for Medical Research NIH-funded |
| Lab location | 1 site (Camden, United States) |
| Project start | March 15, 2015 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $1,295,107 |
| NIH project number | 5U42GM115336-12 |
| Project ID | NIH-11414866 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with inherited disorders or chromosomal abnormalities, as well as healthy individuals and those from diverse geographic backgrounds, may indirectly benefit through future discoveries.
✕Less likely to help
The project does not test therapies or enroll patients directly; benefits arise from improved research resources.
What this research studies
Coriell Institute proposes to maintain and expand the HGCR, a centralized resource of well-characterized human biospecimens. The project focuses on collection, validation, storage, and distribution of cell lines and DNA to researchers, with added genetic services upon request. This effort supports biomedical research, education, and efforts to understand and prevent human genetic diseases. The repository serves investigators nationwide and internationally, ensuring high standards of relevance and quality for future studies.
Why it matters
Potential benefit: Researchers will have ready access to well-characterized human biospecimens to advance understanding and treatment of genetic diseases.
How similar studies have gone: The HGCR has a long history and established utility for genetic research and education, demonstrating ongoing value for investigators.
Where this research is happening
-
Coriell Institute for Medical Research
Camden, United States Active
Researchers
- Principal investigator: Turan, Nahid — Coriell Institute for Medical Research
- Study coordinator: Turan, Nahid
Related research
Other NIH-funded projects on the same topics.
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Mysterious DNA marks in sperm and eggs: how sex shapes germline methylation
This grant looks at how DNA methylation patterns in sperm and eggs become different between the sexes and why that matters for fertility and healthy offspring.
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Centralized bank of human cell lines and DNA for biomedical research
A national repository funded by NIH provides high-quality human cell lines and DNA from people with inherited disorders and diverse backgrounds to researchers.
-
Human Genetic Cell Repository for Biomedical Research
A national resource center will keep and expand a library of well-documented human cell lines and DNA from people with inherited disorders and diverse backgrounds to help researchers study genetic diseases.
-
NIGMS Human Genetic Cell Repository for Biomedical Research
This NIH grant supports Coriell to maintain and expand a centralized collection of human cell lines and DNA from people with inherited disorders and diverse backgrounds to speed biomedical discoveries.
-
NHGRI Sample Repository for Human Genetic Research
A national resource is renewed to provide a large, publicly accessible collection of human biospecimens and genomic data to support trustworthy genetic research.
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NRF2-ACSS2 Axis in Alcohol-Linked Esophageal Health
This grant studies how a cellular power switch (NRF2-ACSS2) drives alcohol-related changes in esophageal cells and tissue, with findings that could guide future prevention.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.