Central public collection of human DNA and cell samples
Official title: NHGRI Sample Repository for Human Genetic Research
Funded at Coriell Institute for Medical Research · NIH-11124042 · Data updated 2026-11-12
A public resource that stores and shares DNA, cell lines, and other biospecimens from diverse people to help researchers studying human genetics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Coriell Institute for Medical Research NIH-funded |
| Lab location | 1 site (Camden, United States) |
| Project start | August 8, 2016 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $864,373 |
| NIH project number | 5U24HG008736-10 |
| Project ID | NIH-11124042 on NIH RePORTER |
Who could benefit from this research
✓Could help
People who are willing to donate biospecimens (blood or tissue), agree to broad genomic research use and data sharing, and can provide required consent and collection procedures are suitable contributors.
✕Less likely to help
Individuals seeking immediate personal medical treatment or direct clinical results are unlikely to gain direct health benefit from contributing samples to this repository.
What this research studies
This repository collects donated blood, DNA, RNA, and renewable cell lines from people around the world and links them with standardized information and consent for broad research use. Staff carefully characterize, quality-control, store, and catalog samples so researchers can request whole DNA, high molecular weight DNA, RNA, cell pellets, or custom sample plates. The resource includes major collections like the 1000 Genomes samples and is expanding to include contributions from the Human Pangenome Reference Consortium. Samples and custom preparations are distributed to qualified researchers worldwide to support many kinds of genetic and genomic studies.
Why it matters
Potential benefit: By making high-quality, well-characterized human biospecimens widely available, the repository can speed discoveries about genetic causes of disease and support development of better diagnostics and therapies.
How similar studies have gone: Yes — established public biorepositories (including the 1000 Genomes collection) have supported thousands of published studies, showing this model reliably advances genetic research.
Where this research is happening
-
Coriell Institute for Medical Research
Camden, United States Active
Researchers
- Principal investigator: Scheinfeldt, Laura — Coriell Institute for Medical Research
- Study coordinator: Scheinfeldt, Laura
Related research
Other NIH-funded projects on the same topics.
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Mysterious DNA marks in sperm and eggs: how sex shapes germline methylation
This grant looks at how DNA methylation patterns in sperm and eggs become different between the sexes and why that matters for fertility and healthy offspring.
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NIGMS Human Genetic Cell Repository Support
A national biobank helps scientists by keeping high-quality human cell lines and DNA from people with genetic differences and healthy individuals for research and teaching.
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Centralized bank of human cell lines and DNA for biomedical research
A national repository funded by NIH provides high-quality human cell lines and DNA from people with inherited disorders and diverse backgrounds to researchers.
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Human Genetic Cell Repository for Biomedical Research
A national resource center will keep and expand a library of well-documented human cell lines and DNA from people with inherited disorders and diverse backgrounds to help researchers study genetic diseases.
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NIGMS Human Genetic Cell Repository for Biomedical Research
This NIH grant supports Coriell to maintain and expand a centralized collection of human cell lines and DNA from people with inherited disorders and diverse backgrounds to speed biomedical discoveries.
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NHGRI Sample Repository for Human Genetic Research
A national resource is renewed to provide a large, publicly accessible collection of human biospecimens and genomic data to support trustworthy genetic research.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.