Sponsor or institution

Clinical trials and research at Central Arkansas Veterans Hlthcare Sys

• 25NIH research projects

NIH-funded research (25)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Collaborative depression care for Veterans Living with HIV in VA clinics

  A program to help people living with HIV and depression get better care by bringing a proven depression treatment approach into VA HIV clinics.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11458133

• Implementation of a new approach to moral injury in kids: helping MIS symptoms with a group program

  A clinician-led group program called Building Spiritual Strength is being tested to help children and youth affected by moral injury symptoms.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11445640

• Understanding Drug-Resistant Multiple Myeloma to Stop Relapse

  Researchers are studying why some myeloma cells resist treatment and how to create new therapies to prevent relapse.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11428791

• Antibodies that neutralize oxidized fats to protect bone health

  This project will see if boosting natural antibodies that neutralize oxidized phospholipids can help prevent age-related bone loss and osteoporosis.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11264782

• Targeting drug-resistant multiple myeloma cells

  This project looks for markers of myeloma cells that survive treatment and uses them to create new therapies for people whose multiple myeloma comes back after treatment.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11206942

• Using approved medicines to break up harmful protein clumps in Alzheimer's

  Testing whether already-approved drugs can disrupt sticky tau and amyloid protein clumps that form in people with Alzheimer's disease.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11206875

• Team-based depression care for Veterans living with HIV

  This project brings a proven, team-based program into VA HIV clinics using local clinic champions and peer learning so Veterans with HIV can get better, coordinated depression care.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11199638

• Clinician and chaplain support program for Veterans with moral injury

  This program offers coordinated help from VA mental health clinicians and chaplains to Veterans dealing with guilt, shame, and isolation linked to moral injury.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11196728

• Testing a new way to connect Veterans with alcohol care services

  This study is testing a new way to help Veterans who drink too much and may also be dealing with issues like PTSD or depression, by connecting them to the right alcohol treatment services they need to feel better.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11145606

• Reducing unnecessary use of levothyroxine medication

  This study is looking into why some people are given thyroid medication called levothyroxine when they might not really need it, and it aims to help doctors make better decisions so that only those who truly need the medicine get it, ultimately leading to safer and more effective treatment for patients.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11111033

• Helping Veterans stay on medication for opioid addiction using health data

  This project uses VA health records and AI to predict which Veterans on medication for opioid use disorder might stop treatment so care teams can offer extra support.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11086153

• Improving bone health and fracture recovery in aging Veterans

  This study is looking for new ways to help older Veterans strengthen their bones and prevent osteoporosis by finding better methods to use a hormone that helps with bone growth.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11061873

• Improving bone health and healing in aging Veterans

  This study is looking for new ways to help older Veterans strengthen their bones and heal better, so they can avoid fractures and stay active and pain-free.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11051685

• Investigating antibodies that target oxidized phospholipids to improve bone health in older adults

  This study is looking at how a special antibody might help prevent bone loss as we age, which could be really helpful for older adults dealing with osteoporosis.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-11009539

• Investigating lipid metabolism and signaling in cardiovascular diseases

  This study is looking at how certain fats in the body affect heart and metabolic health, especially in veterans, to find new ways to diagnose and treat heart diseases like atherosclerosis and calcific aortic valve disease.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10951548

• Investigating enzymes that cause cell death in kidney and cancer cells

  This study is looking at how certain enzymes can cause cell death after injuries to tissues, like those from drugs or diseases, and aims to find ways to protect kidney and cancer cells from damage, which could lead to better treatments for patients.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10950293

• Investigating the link between metal exposure and prostate cancer in veterans

  This study is looking at how being around certain metals, like arsenic and lead, might raise the chances of getting prostate cancer in veterans, and it hopes to find helpful clues that could improve prevention and treatment for them.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10950287

• Investigating protein aggregation in neurodegenerative diseases like Alzheimer's and Parkinson's

  This study is looking at how clumps of proteins might play a role in diseases like Alzheimer's and Parkinson's, and it's testing some new drugs that could help stop these clumps from forming, with the hope of finding better treatments for people affected by these conditions.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10946714

• Strategies to engage rural veterans in preventing suicide

  This study is all about finding better ways to help veterans, especially those in rural areas, get the support they need to prevent suicide by involving them and their families in choosing the best healthcare options for them.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10934530

• Identifying drug resistance in multiple myeloma to improve treatment options

  This study is looking for special markers in tough multiple myeloma cells that don't respond to treatment, so we can create better therapies to help patients avoid relapse and improve their chances of recovery.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10925595

• Using existing drugs to target protein interactions involved in Alzheimer's disease

  This study is looking at how certain approved medications might help break up harmful protein clumps in the brain that are linked to Alzheimer's disease, with the hope of finding new treatments that could slow down the progression of the condition.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10925593

• Investigating how metals affect prostate cells and cancer risk

  This study is looking at how exposure to metals like lead and arsenic might affect prostate cells and increase the risk of prostate cancer, using animal models and urine samples from patients to better understand this connection.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10881736

• Collaboration between mental health clinicians and chaplains to help veterans with moral injury

  This study is exploring a new way to help veterans who are struggling with feelings of guilt and shame by bringing together mental health professionals and chaplains to support their healing and reintegration into the community.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10753048

• Improving depression care for veterans with HIV in clinics

  This study is looking at how to better help veterans with HIV who are also dealing with depression by training local healthcare providers to offer mental health support right where they get their HIV care, making it easier for them to feel better.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10397976

• Investigating how serum amyloid A connects inflammation and blood clotting

  This study is looking at how a protein called serum amyloid A (SAA) connects inflammation to blood clotting, especially in people with heart and blood vessel issues, to find new ways to prevent serious problems like heart attacks and strokes.

  NIH research Central Arkansas Veterans Hlthcare Sys · North Little Rock, United States · NIH-10106461

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