Investigating lipid metabolism and signaling in cardiovascular diseases
Official title: BLRD Research Career Scientist Award Application
Funded at Central Arkansas Veterans Hlthcare Sys · NIH-10951548 · Data updated 2026-11-12
This study is looking at how certain fats in the body affect heart and metabolic health, especially in veterans, to find new ways to diagnose and treat heart diseases like atherosclerosis and calcific aortic valve disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Central Arkansas Veterans Hlthcare Sys NIH-funded |
| Lab location | 1 site (North Little Rock, United States) |
| Project start | October 1, 2023 |
| Project end | September 30, 2028 |
| Funding year | 2025 |
| NIH project number | 5IK6BX006469-02 |
| Project ID | NIH-10951548 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include veterans and active-duty military personnel who are at risk for or suffering from cardiovascular diseases.
✕Less likely to help
Patients who do not have cardiovascular diseases or related risk factors may not benefit from this research.
What this research studies
This research focuses on understanding how lipid metabolism and signaling pathways contribute to cardiovascular and metabolic diseases, particularly in veterans. The principal investigator has been studying the PLPP3 lipid phosphatase gene, which is linked to heritable cardiovascular disease risk. The research aims to identify new diagnostic and therapeutic approaches for conditions like atherosclerosis and calcific aortic valve disease, which are more prevalent in veterans. By exploring these pathways, the study seeks to improve patient outcomes through better management of these diseases.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for veterans suffering from cardiovascular diseases.
How similar studies have gone: Previous research has shown success in exploring lipid metabolism and signaling pathways in cardiovascular diseases, indicating that this approach is promising.
Where this research is happening
-
Central Arkansas Veterans Hlthcare Sys
North Little Rock, United States Active
Researchers
- Principal investigator: Morris, Andrew J — Central Arkansas Veterans Hlthcare Sys
- Study coordinator: Morris, Andrew J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.