Sponsor or institution
Clinical trials and research at Beckman Research Institute/city of Hope
As of November 12, 2026, Find a Trial lists 335 NIH-funded research projects at this institution, with $196.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 335NIH research projects
NIH-funded research (newest 40 of 335)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Targeting the protein-assembly that drives AML growth
Aiming to slow or stop acute myeloid leukemia by blocking how cancer cells make proteins.
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Metformin for reversing accelerated aging in young adults with metabolic health issues
A practical plan to use metformin to help 18- to 35-year-olds with insulin resistance improve metabolic health and slow aging.
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PIN1-targeted therapy for pancreatic cancer
A team is developing new PIN1 inhibitors to treat pancreatic cancer that tends to resist current therapies.
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DNA mismatch repair defects and anti-tumor immunity in cancer
Researchers are studying how defects in a DNA repair system affect the body’s immune response to tumors, to improve cancer treatments that use the immune system.
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Understanding how skin cancer-associated fibroblasts affect immune detection in early mycosis fungoides
This grant investigates how certain skin cells in early mycosis fungoides might help the cancer hide from the immune system, with findings aiming to improve future patient care.
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Small-molecule and biologic treatments for glioblastoma using targeted brain delivery
A new approach aims to use FPS-ZM1 to shrink brain swelling and support immunotherapy for glioblastoma, potentially helping patients recover after surgery.
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Integrated Islet Distribution Program supports access to human pancreatic islets for diabetes research
This grant helps provide researchers with human pancreatic islets and related tissues to study diabetes, aiming to accelerate better understanding and treatments for adults with diabetes.
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Exosome-based microRNA biomarkers for early, non-invasive detection of pancreatic cancer
A study to develop a blood test that uses tiny RNA signals in exosomes to detect pancreatic cancer early, aiming to help people at risk or with early disease.
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Exosome-based microRNA biomarkers for early detection of pancreatic cancer
A patient-friendly look at a study using tiny blood-based RNA markers inside exosomes to catch pancreatic cancer early without invasive procedures.
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Understanding why Latino children have a higher risk of childhood ALL
This project looks at why Latino children are more likely to develop acute lymphoblastic leukemia and whether genetic ancestry plays a role, with the goal of improving prevention and outcomes.
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Genetic Regulation of Gene Expression in Hispanic/Latino Cord Blood
This project looks at how genetic differences shape gene activity in newborns of Hispanic/Latino heritage using cord blood, to better understand links to disease.
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PK resource core to speed anticancer drug development
A national collaboration of two cancer center labs provides advanced drug-kinetics testing to support new anticancer agents in early clinical trials.
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Early-stage cancer drugs testing across six California centers
Researchers at six leading cancer centers are teaming up to test new cancer therapies in early-stage clinical trials to help patients with cancer.
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How the molecule YTHDC1 affects blood stem cells and leukemia
This work looks at whether higher levels of the molecule YTHDC1 change how blood stem cells behave and contribute to acute myeloid leukemia.
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Short form of TET1 linked to myelodysplastic syndromes (MDS)
Looks at whether a shorter version of the TET1 protein disrupts blood stem cells and contributes to myelodysplastic syndromes in people with or at risk for MDS.
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Pancreatic beta cells, oxidative stress, and gestational diabetes
A study is exploring how oxidative stress and changes in pancreatic beta cells during pregnancy may contribute to gestational diabetes and future diabetes risk for both mother and baby.
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Metabolic DNA Damage and Obesity-Linked Prostate Cancer Progression
A study to understand how obesity-related metabolism and a cancer cell’s DNA damage drive the progression of aggressive prostate cancer in men.
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Decoding heart cell subtypes to understand and treat heart failure
A patient-facing look at a grant that aims to map heart muscle cell types to uncover why high blood pressure can lead to heart failure and guide better therapies.
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Nucleotide Support to Help Heart Cells Heal After a Heart Attack
A research project will test whether giving specific nucleotides can boost heart muscle cells to grow and repair after a heart attack in animal models and larger animals.
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Integration of epidemiology, pathology, immunology and outcomes in colorectal cancer
A physician-scientist team is using artificial intelligence on colorectal cancer tissue images to improve diagnosis, prognosis, and treatment decisions for patients.
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Exercise therapy to slow progression in localized prostate cancer on active surveillance
A study will test whether a structured home-based exercise program helps men with localized prostate cancer who are on active surveillance avoid moving to treatment or worsening, compared with usual care.
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Dietary fiber, gut bacteria, and gut transplant health
A nutrition-focused NIH grant looks at how fiber and gut bacteria affect the health of people who have received bone marrow or stem cell transplants.
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Akkermansia muciniphila: how gut bacteria and capsules influence GVHD after stem cell transplant
This project looks at how a common gut bacterium, Akkermansia muciniphila, and its genetic differences might affect GVHD risk after stem cell transplantation in humans and mice.
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Mucin-preserving strategies to reduce complications after stem cell transplant
A patient-facing overview of a program aiming to protect gut mucus and reduce treatment-related complications after stem cell transplants.
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Genetics Core for Mucin-Degrading Bacteria
A team will build a genetics core to study how gut bacteria like Akkermansia and Bacteroides break down mucus, with potential to improve health in people undergoing stem cell transplant.
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Administrative, Biostatistics, Clinical and Bionutrition Core for Cancer Center Program
A cancer center project core provides leadership, biostatistical and bionutrition support and collects patient data and biospecimens to help three related research projects explore how gut bacteria affect treatment side effects and test new ways to reduce them.
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Mucus-loving gut bacteria and gut toxicity after stem cell transplant
This grant studies how gut bacteria that eat mucus influence toxicities after hematopoietic cell transplantation and what can be done to keep patients safer.
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Leading national and City of Hope clinical trials in lymphoma care
A clinician-scientist at City of Hope leads and supports national and local lymphoma clinical trials to bring new therapies to patients with Hodgkin and non-Hodgkin lymphoma.
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Outreach core to connect research with communities in cancer work
A center-led program works to bring community input into cancer research and help share findings with patients and communities.
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Core 2: A program to train the next generation in cancer drug development
A partnership program to build training, resources, and curriculum so researchers at UCR and City of Hope can move cancer ideas toward clinical trials and develop future drug developers.
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Planning and Evaluation Core for a cancer center partnership
A planning and evaluation core helps a California cancer center partnership track progress, share lessons, and strengthen education and collaboration for better cancer research and drug development.
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Capacity Building Core: Growing City of Hope-UCR cancer research collaborations
This grant funds a capacity-building program to help City of Hope and UC Riverside researchers, especially early-career investigators, work together on cancer research and clinical trials.
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Administrative Core for UCR–CoHCCC U54 partnership
A leadership and coordination grant to help two cancer centers work together more effectively on planning, oversight, and community engagement to advance cancer research and clinical trials.
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Drug development and capacity building partnership for cancer research
A joint effort between UC Riverside and City of Hope to build resources, training, and collaboration so researchers can move promising cancer ideas toward new drugs and clinical trials.
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Exosome-based microRNA biomarkers for early, non-invasive detection of pancreatic cancer
A study to test a blood test that looks at tiny RNA bits in exosomes to detect pancreatic cancer early without surgery or invasive procedures.
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Microbial therapies to block cancer cell nutrient scavenging in bladder and other Kras-driven cancers
A cancer-focused research project tests how microbes could help shut down a key nutrient-pumping process in bladder cancer and other Kras-driven tumors.
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Early pancreatic cancer detection using an exosome microRNA blood test
A blood test that looks at tiny particles called exosomes and the microRNA they carry to spot pancreatic cancer early in people at risk.
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Non-invasive blood test using exosome microRNAs to find pancreatic cancer early
Develops a blood test that reads tiny RNA messages inside exosomes to detect early pancreatic cancer in people at risk.
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Promoting heat-loving fat cells to help burn energy
Aims to help people lose weight by making body fat more like energy-burning beige fat using a new approach linked to a natural sugar polymer.
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Gut bacteria that break down mucus and transplant complications
Researchers are looking at whether mucus-eating gut bacteria and certain antibiotics make gut damage and infections worse for people getting allogeneic blood stem cell transplants.
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