Understanding how skin cancer-associated fibroblasts affect immune detection in early mycosis fungoides

Who could benefit from this research

What this research studies

The project uses advanced lab methods to study skin samples from MF patients at different stages and backgrounds. Researchers will perform single-cell RNA sequencing and spatial RNA transcriptomics to map CAF subtypes and their locations. They will connect these cellular patterns to how the disease progresses and how patients’ demographics may influence these processes. The training plan includes mentorship and hands-on experience in molecular techniques and computational analysis to translate these insights into potential biomarkers.

Why it matters

Where this research is happening

• Beckman Research Institute/city of Hope
  Duarte, United States Active

Researchers

• Principal investigator: Johnson, Courtney Michele — Beckman Research Institute/city of Hope
• Study coordinator: Johnson, Courtney Michele

Related research

Other NIH-funded projects on the same topics.

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  NIH research Johns Hopkins University · Baltimore, United States · NIH-10948591

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.