Improving lung health for people recovering from tuberculosis
Official title: TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity
Funded at Johns Hopkins University · NIH-10915401 · Data updated 2026-11-12
This study is looking at two different home exercise programs to help people who have finished tuberculosis treatment breathe better and feel healthier, while also making sure these programs are easy to use and affordable for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $587,913 |
| NIH project number | 5R01AI169588-02 |
| Project ID | NIH-10915401 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who have recently completed treatment for tuberculosis.
✕Less likely to help
Patients who are currently undergoing tuberculosis treatment or those with severe comorbidities that prevent participation in rehabilitation may not benefit from this research.
What this research studies
This research focuses on developing and testing a pulmonary rehabilitation program aimed at preventing respiratory issues in individuals who have completed tuberculosis treatment. It will compare two different home-based rehabilitation approaches to see which is more effective in improving lung function and overall health. The study will also explore how well these programs are delivered and their cost-effectiveness, ensuring that they can be implemented in resource-limited settings. Patients will receive support and guidance to help them engage in exercises and activities that promote better lung health.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life and lung health for tuberculosis survivors.
How similar studies have gone: Previous research has shown that pulmonary rehabilitation can be effective for chronic lung diseases, but this specific approach for post-tuberculosis recovery is novel.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Golub, Jonathan E. — Johns Hopkins University
- Study coordinator: Golub, Jonathan E.
Related research
Other NIH-funded projects on the same topics.
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Pulmonary rehabilitation to reduce breathing problems after tuberculosis
A program of guided exercise and breathing training to help adults who have recovered from TB breathe better and feel healthier.
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Pulmonary rehab to reduce breathing troubles after TB
A program of pulmonary rehabilitation is being studied to help adults who have completed TB treatment avoid ongoing lung problems and improve daily breathing.
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Pulmonary rehabilitation to reduce breathing problems after TB
A program of supervised breathing and exercise therapy is tested to see if it helps people who have recovered from tuberculosis breathe better and feel better.
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Pulmonary rehabilitation to prevent post-TB lung problems
This project offers and compares two home-based breathing and exercise programs for adults with TB to help prevent long-term lung problems after treatment.
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Pulmonary rehabilitation to prevent lung problems after tuberculosis
Two home-based breathing and exercise programs are offered to adults being treated for tuberculosis to help protect lung health after treatment.
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Pulmonary rehabilitation to prevent lung problems after tuberculosis
This project compares two home-based breathing and exercise programs given during TB treatment to help adults prevent long-term lung problems after pulmonary tuberculosis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.