Improving lung health for people recovering from tuberculosis

TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity

NIH-funded research Johns Hopkins University · NIH-10915401

This study is looking at two different home exercise programs to help people who have finished tuberculosis treatment breathe better and feel healthier, while also making sure these programs are easy to use and affordable for everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10915401 on NIH RePORTER

What this research studies

This research focuses on developing and testing a pulmonary rehabilitation program aimed at preventing respiratory issues in individuals who have completed tuberculosis treatment. It will compare two different home-based rehabilitation approaches to see which is more effective in improving lung function and overall health. The study will also explore how well these programs are delivered and their cost-effectiveness, ensuring that they can be implemented in resource-limited settings. Patients will receive support and guidance to help them engage in exercises and activities that promote better lung health.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who have recently completed treatment for tuberculosis.

Not a fit: Patients who are currently undergoing tuberculosis treatment or those with severe comorbidities that prevent participation in rehabilitation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the quality of life and lung health for tuberculosis survivors.

How similar studies have performed: Previous research has shown that pulmonary rehabilitation can be effective for chronic lung diseases, but this specific approach for post-tuberculosis recovery is novel.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Chronic lung disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.