Pulmonary rehabilitation to prevent lung problems after tuberculosis
TB PuRe : Pulmonary rehabilitation to reduce post-tuberculosis morbidity
Two home-based breathing and exercise programs are offered to adults being treated for tuberculosis to help protect lung health after treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11415440 on NIH RePORTER |
What this research studies
If you are an adult receiving TB treatment, you may be offered one of two home-based pulmonary rehabilitation programs that combine aerobic exercise, breathing techniques, and coach support during treatment. The project will compare how well each program prevents lung problems after TB by measuring breathing, symptoms, and daily activity following treatment. Researchers will also examine clinic organization, how closely coaches deliver the programs, and how patients follow the exercises. Costs and budget impact will be compared to determine which approach is most affordable and scalable in resource-limited settings.
Who could benefit from this research
Good fit: Adults (21+) currently receiving TB treatment who can perform light exercise and are willing to follow a home-based rehabilitation program are the ideal candidates.
Not a fit: People under 21, those who are too sick to do the exercises, or those with other severe medical conditions may not receive benefit from these programs.
Why it matters
Potential benefit: If successful, these programs could reduce long-term lung damage and improve breathing and daily quality of life for people who survive TB.
How similar studies have performed: Pulmonary rehabilitation has helped people with chronic lung diseases like COPD, but applying home-based PR during TB treatment to prevent post-TB lung problems is largely new and unproven.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Golub, Jonathan E. — Johns Hopkins University
- Study coordinator: Golub, Jonathan E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.