Improving Care for Critically Ill Children
Official title: Collaborative Pediatric Critical Care Research Network - Clinical Site
Funded at Duke University · NIH-11181001 · Data updated 2026-11-12
This effort brings together medical centers to offer cutting-edge care and studies for children who are very sick.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | August 18, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $158,514 |
| NIH project number | 5RL1HD107784-05 |
| Project ID | NIH-11181001 on NIH RePORTER |
Who could benefit from this research
✓Could help
Critically ill children, particularly those aged 0-11 years, who are admitted to a pediatric intensive care unit, are ideal candidates for potential participation in related studies.
✕Less likely to help
Patients who are not critically ill or are outside the specified age range may not directly benefit from this particular research network's activities.
What this research studies
Our goal is to join a larger group of hospitals dedicated to improving how we care for critically ill children. By working together, we can offer more advanced treatment options and participate in important studies that help us learn the best ways to help young patients. This collaboration ensures that children in our region have access to the latest medical advancements and research opportunities.
Why it matters
Potential benefit: If successful, this collaboration could lead to better treatments and improved health outcomes for critically ill children.
How similar studies have gone: This site has a strong track record, having enrolled over 400 critically ill children in 15 clinical studies through similar multicenter research networks in recent years.
Where this research is happening
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Duke University
Durham, United States Active
Researchers
- Principal investigator: Hornik, Christoph — Duke University
- Study coordinator: Hornik, Christoph
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
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Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
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Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
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Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
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Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.