Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
Official title: Collaborative Pediatric Critical Care Research Network - Clinical Site
Funded at University of Minnesota · NIH-11564121 · Data updated 2026-11-12
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 18, 2021 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $155,000 |
| NIH project number | 3RL1HD107782-05S1 |
| Project ID | NIH-11564121 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children aged 0-11 who are critically ill with sepsis and organ dysfunction across participating centers could be eligible.
✕Less likely to help
Some children may not have sepsis or may not meet specific phenotype criteria at enrollment, limiting direct benefit.
What this research studies
This grant funds a site within a national pediatric critical care network to support clinical trials and observational studies in children with severe sepsis. It aims to use rapid immune-phenotype diagnostics to personalize treatment for kids with organ dysfunction due to sepsis. The site collaborates with other centers to collect data, apply precision immunomodulation approaches, and implement interventional protocols designed for individual patient biology. The overall goal is to reduce mortality and improve organ recovery by moving from one-size-fits-all care to personalized strategies.
Why it matters
Potential benefit: If successful, this work could lead to more effective, individualized treatments for children with septic shock and organ failure.
How similar studies have gone: Previous multi-center pediatric sepsis research has shown that biology-based tailoring is feasible and beneficial in identified subgroups.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Steiner, Marie E — University of Minnesota
- Study coordinator: Steiner, Marie E
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
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Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
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Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
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Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
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Collaborative Pediatric Critical Care Network study
A national network is testing personalized immune treatments for critically ill children with sepsis in multiple hospitals.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.