Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
Official title: Collaborative Pediatric Critical Care Research Network - Clinical Site
Funded at Baylor College of Medicine · NIH-11565056 · Data updated 2026-11-12
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 18, 2021 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $160,500 |
| NIH project number | 3RL1HD107780-05S1 |
| Project ID | NIH-11565056 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children aged 0-11 with sepsis-induced MODS at participating pediatric centers.
✕Less likely to help
Children without sepsis or without MODS may not benefit from the personalized protocols.
What this research studies
This grant supports a pediatric critical care research network that runs multi-center studies and trials in children with sepsis-related organ failure. It focuses on delivering personalized treatments based on a child’s unique immune response, rather than a one-size-fits-all approach. The work builds rapid lab diagnostics to identify immune phenotypes and uses interventional protocols tailored to each patient’s condition across participating hospitals.
Why it matters
Potential benefit: If successful, it could lead to more effective, individualized treatments for septic children and better survival and recovery.
How similar studies have gone: Previous findings suggest distinct immune phenotypes in septic children, supporting the potential of phenotype-guided care.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Akcan Arikan, Ayse — Baylor College of Medicine
- Study coordinator: Akcan Arikan, Ayse
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
-
Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
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Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
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Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
-
Collaborative Pediatric Critical Care Network study
A national network is testing personalized immune treatments for critically ill children with sepsis in multiple hospitals.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.