Improving Care for Critically Ill Children
Official title: Collaborative Pediatric Critical Care Research Network - Clinical Site
Funded at Children's Hosp of Philadelphia · NIH-11179178 · Data updated 2026-11-12
This program helps doctors at Children's Hospital of Philadelphia work together to find better ways to care for very sick children.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 18, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $176,000 |
| NIH project number | 5RL1HD107777-05 |
| Project ID | NIH-11179178 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children aged 0-11 years old who are critically ill, particularly those with severe infections like sepsis, may be candidates for future studies related to this research.
✕Less likely to help
Children who are not critically ill or do not have conditions related to the specific areas of focus within the network may not directly benefit from this particular research.
What this research studies
Children's Hospital of Philadelphia is a key part of a national network dedicated to improving care for critically ill children. As a clinical site, CHOP helps conduct important studies to find new and better treatments for young patients in intensive care. One major focus is a large clinical trial exploring personalized treatments for children with sepsis, a severe infection that can lead to organ failure. This trial aims to tailor treatments to each child's unique immune response, hoping to improve their chances of recovery and overall health.
Why it matters
Potential benefit: Successful outcomes from this work could lead to more effective, personalized treatments for critically ill children, potentially saving lives and improving recovery.
How similar studies have gone: This network has a long history of conducting clinical trials to advance pediatric critical care, building on previous findings to develop new approaches.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Berg, Robert Allen — Children's Hosp of Philadelphia
- Study coordinator: Berg, Robert Allen
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
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Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
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Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
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Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
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Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.