Electronic tools to help doctors manage high blood pressure in kidney disease patients
Official title: Electronic Tools to Increase Recognition and Improve Primary Care Management for Hypertension in Chronic Kidney Disease: A Multi-site Randomized Clinical Trial
Funded at Brigham and Women's Hospital · NIH-11416726 · Data updated 2026-11-12
A multi-site study tests an electronic decision-support tool within primary care to help treat high blood pressure in adults with chronic kidney disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2018 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $833,279 |
| NIH project number | 5R01DK116898-07 |
| Project ID | NIH-11416726 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older with chronic kidney disease who visit primary care clinics and could benefit from BP management using evidence-based treatments.
✕Less likely to help
Patients without CKD or those not under primary care management for hypertension may not benefit from this tool.
What this research studies
This project builds on a previously tested computer tool that uses patient data from electronic health records to give primary care clinicians clear, evidence-based recommendations for managing hypertension in people with chronic kidney disease. It will implement and test the tool across three health systems to see if it consistently lowers systolic blood pressure and increases use of proven therapies. The team will also update the tool to address medication adherence and include new treatment recommendations, such as SGLT2 inhibitors. By making the tool user-friendly and aligned with clinic workflows, the study aims to improve how CKD and hypertension are managed in real-world primary care settings.
Why it matters
Potential benefit: If successful, patients with CKD could have better blood pressure control and reduced risk of kidney and cardiovascular complications through better-guided primary care management.
How similar studies have gone: Previous work showed the tool lowered systolic BP and increased appropriate RAASi therapy in a CKD population; this study tests generalizability.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Samal, Lipika — Brigham and Women's Hospital
- Study coordinator: Samal, Lipika
Related research
Other NIH-funded projects on the same topics.
-
Electronic tools to help doctors find and treat high blood pressure in people with chronic kidney disease
This project uses electronic health record alerts and recommendations to help primary care doctors better find and manage high blood pressure in adults with chronic kidney disease.
-
HEARTS hypertension and diabetes care in Guatemala
This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.
-
Personalized CKD-MBD care using systems biology and AI
A patient-facing program aims to tailor mineral-balance therapy for people with chronic kidney disease by using a computer model and smart decision rules to predict who will respond best to treatments.
-
Mitigating DKA in people with type 1 diabetes and kidney disease using SGLT1/2 inhibitors
This project tests a new way to prevent dangerous diabetic ketoacidosis in people with type 1 diabetes and chronic kidney disease who are using SGLT inhibitors, by tracking ketones in real time and combining glucose-keton data for safer therapy.
-
Chronic Kidney Disease in Children: following young people as they grow up with CKD
A long-term study in kids with chronic kidney disease tracks kidney function and heart health as they transition into adulthood.
-
Chronic Kidney Disease in Children follow-up study
A long-term study that follows kids with kidney disease as they grow into young adults, collecting health data from home and official records.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.