NIH-funded research R01 grant

Electronic tools to help doctors find and treat high blood pressure in people with chronic kidney disease

Official title: Electronic Tools to Increase Recognition and Improve Primary Care Management for Hypertension in Chronic Kidney Disease: A Multi-site Randomized Clinical Trial

Funded at Brigham and Women's Hospital · NIH-11139070 · Data updated 2026-11-12

This project uses electronic health record alerts and recommendations to help primary care doctors better find and manage high blood pressure in adults with chronic kidney disease.

More Hypertension research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 1, 2018
Project endJune 30, 2030
Funding year2025
Award (this year)$884,371
NIH project number2R01DK116898-06
Project IDNIH-11139070 on NIH RePORTER

Who could benefit from this research

Could help

Adults with chronic kidney disease who get primary care at one of the participating health systems and have elevated blood pressure or related risk factors are the ideal candidates.

Less likely to help

People without chronic kidney disease, children, those not receiving care at participating clinics, or patients already under specialty nephrology care such as dialysis may not benefit from this project.

What this research studies

If you have chronic kidney disease, this project will add smart reminders and treatment suggestions into your doctor's electronic health record to help them notice and treat high blood pressure. The tools were designed with patients and clinicians in mind and use behavioral prompts to make guideline-recommended actions easier. The team will roll out updated tools across three health systems and run a randomized trial to see how well they work in different clinics. They will also add features to address medicine nonadherence and new guidance about SGLT2 inhibitor medications.

Why it matters

Potential benefit: If successful, this could help lower blood pressure and reduce the risk of kidney and heart complications for people with CKD.

How similar studies have gone: Earlier work by the same team showed the clinical decision support tool reduced systolic blood pressure and increased guideline blood-pressure medication prescribing, but broader testing across multiple health systems is still needed.

Where this research is happening

  • Brigham and Women's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Samal, Lipika — Brigham and Women's Hospital
  • Study coordinator: Samal, Lipika

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.