NIH-funded research U01 cooperative agreement

Chronic Kidney Disease in Children: following young people as they grow up with CKD

Official title: Chronic Kidney Disease in Children (CKiD V)

Funded at Children's Mercy Hosp (Kansas City, Mo) · NIH-11588599 · Data updated 2026-11-12

A long-term study in kids with chronic kidney disease tracks kidney function and heart health as they transition into adulthood.

More Kidney Disease research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionChildren's Mercy Hosp (Kansas City, Mo)
NIH-funded
Lab location1 site (Kansas City, United States)
Project startSeptember 30, 2003
Project endJuly 31, 2028
Funding year2026
Award (this year)$50,000
NIH project number3U01DK066143-24S2
Project IDNIH-11588599 on NIH RePORTER

Who could benefit from this research

Could help

Children and adolescents with CKD, including those transitioning to adulthood, may be eligible to participate.

Less likely to help

Patients without CKD or outside the 14–17 age window may not directly benefit from this study.

What this research studies

This project will continue following an existing group of children with CKD and enroll 14- to 17-year-olds to boost understanding of how kidney function changes during adolescence and into young adulthood. Data will be collected remotely through home labs, digital surveys, and electronic health records, with care coordinated by national labs and REDCap for streamlined reporting. Participants may enter information online or via mobile devices, and researchers will examine risk factors, including puberty-related changes and acute kidney injuries, that influence disease progression. The study aims to use machine learning to combine clinical data and social factors to predict individual kidney and cardiovascular outcomes.

Why it matters

Potential benefit: If successful, the study could improve how CKD in youth is monitored and managed, potentially slowing disease progression and reducing cardiovascular risk as they grow older.

How similar studies have gone: The CKiD program has previously shown valuable insights into pediatric CKD, and the renewal aims to enhance predictive power with new age groups and remote data collection.

Where this research is happening

  • Children's Mercy Hosp (Kansas City, Mo)
    Kansas City, United States
    Active

Researchers

  • Principal investigator: Warady, Bradley Alan — Children's Mercy Hosp (Kansas City, Mo)
  • Study coordinator: Warady, Bradley Alan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.