NIH-funded research NIH-funded research

Creating an online mindfulness program for adults experiencing cognitive decline

Official title: Development of an online mindfulness training program for adults with subjective cognitive decline

Funded at Ohio State University · NIH-11063290 · Data updated 2026-11-12

This study is testing an online mindfulness program to help adults who feel their thinking skills are slipping, with the hope that it can improve their focus and possibly benefit their brain health, while also comparing it to a group learning about healthy lifestyles.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startApril 1, 2024
Project endMarch 31, 2026
Funding year2025
Award (this year)$505,368
NIH project number5R61AG081982-02
Project IDNIH-11063290 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who are experiencing subjective cognitive decline but do not yet show objective signs of cognitive impairment.

Less likely to help

Patients who do not experience subjective cognitive decline or those with diagnosed Alzheimer's disease or other forms of dementia may not benefit from this research.

What this research studies

This research aims to develop and evaluate an online mindfulness training program specifically designed for adults who report subjective cognitive decline, which is a perceived decline in cognitive abilities without objective evidence. Participants will engage in mindfulness meditation practices to help manage mind-wandering and potentially influence biomarkers associated with Alzheimer's disease. The program will be delivered asynchronously online, allowing participants to access it at their convenience, and will include a comparison group receiving lifestyle education. The goal is to assess the feasibility and acceptability of this intervention for individuals at risk of developing Alzheimer's disease.

Why it matters

Potential benefit: If successful, this research could provide a new, accessible method for individuals with subjective cognitive decline to potentially improve their cognitive health and delay the onset of Alzheimer's disease.

How similar studies have gone: Previous research has shown that mindfulness interventions can be beneficial for cognitive health, suggesting that this approach may be promising for individuals with subjective cognitive decline.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Prakash, Ruchika Shaurya — Ohio State University
  • Study coordinator: Prakash, Ruchika Shaurya

Related research

Other NIH-funded projects on the same topics.

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  • Understanding early signs of cognitive decline using health records and AI

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    NIH research Brigham and Women's Hospital · Boston, United States · NIH-11121163

  • Understanding cognitive decline in older Hispanics/Latinos

    This study is looking at how older Hispanic and Latino individuals feel about their thinking skills and how those feelings connect to actual changes in their memory and thinking, with the goal of spotting early signs of Alzheimer's disease to help with better diagnosis and care.

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  • Investigating how sleep and physical frailty affect cognitive decline in older adults

    This study is looking at how sleep problems and physical weakness in older adults with early signs of memory issues might affect their thinking skills and risk of developing dementia, with the goal of finding ways to help them stay mentally sharp longer.

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  • Understanding early cognitive changes in Alzheimer's disease

    This study is looking at how people notice changes in their thinking skills, especially in the early stages of Alzheimer's, and it’s for anyone who has concerns about their memory; you'll share your thoughts on your cognitive abilities every few months using a device, and the researchers will compare what you say with

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-10762473

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.