Investigating how sleep and physical frailty affect cognitive decline in older adults

Who could benefit from this research

What this research studies

This research focuses on older adults experiencing subjective cognitive decline (SCD) and mild cognitive impairment (MCI) to understand how sleep disturbances and physical frailty contribute to the progression of cognitive decline towards dementia. The study will analyze the relationship between these factors and the presence of Alzheimer’s disease biomarkers, aiming to identify how they interact and influence each other. By examining these connections, the research seeks to uncover potential interventions that could slow down cognitive deterioration in this vulnerable population.

Why it matters

Where this research is happening

• Johns Hopkins University
  Baltimore, United States Active

Researchers

• Principal investigator: Huang, Jing — Johns Hopkins University
• Study coordinator: Huang, Jing

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.