Understanding early signs of cognitive decline using health records and AI

Antecedents and Outcomes of Subjective Cognitive Decline: An Electronic Health Records and Artificial Intelligence Approach

NIH-funded research Brigham and Women's Hospital · NIH-11121163

This study is looking at how electronic health records can help spot early signs of memory problems that might lead to Alzheimer's and similar conditions, so we can find people who need support before they get a formal diagnosis.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11121163 on NIH RePORTER

What this research studies

This research investigates how electronic health records (EHRs) can be used to detect early signs of cognitive decline, specifically subjective cognitive decline (SCD), which may indicate the onset of Alzheimer's disease and related dementias (ADRD). By utilizing advanced artificial intelligence and machine learning techniques, the study aims to identify patients who show early cognitive concerns but have not yet been diagnosed with dementia. The research will analyze large datasets to uncover risk factors and characteristics associated with SCD, ultimately aiming to improve early intervention strategies and participant enrollment in clinical trials.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults who exhibit signs of cognitive decline but have not yet been diagnosed with dementia.

Not a fit: Patients who are already diagnosed with dementia or have significant cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection and intervention for individuals at risk of developing Alzheimer's disease and related dementias.

How similar studies have performed: Previous research has shown promise in using electronic health records and machine learning for early detection of cognitive decline, indicating that this approach has potential for success.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Airway infectionsAlzheimer's disease and related dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.