Condition

Weaning Failure clinical trials and research

• 8Clinical trials
• 7Countries

Newest Weaning Failure clinical trials

All recruiting trials (8)

• heepSync: synchronized electrical stimulation of breathing muscles for adults on mechanical ventilation

  This trial tests whether the heecap heepSync algorithm can safely sync electrical stimulation to breathing muscles in adults on mechanical ventilation.

  Recruiting at 3 sites Tesai Care SL · Barcelona, Barcelona and 2 other locations · NCT07363902

• Characterization of weaning practices in ICUs in Global South countries

  This observational study tests how adult ICU patients on mechanical ventilation who are starting to wean are extubated, observing them for 7 days after extubation and until hospital discharge or death.

  Recruiting Hospital do Coracao · Joinville, Santa Catarina · NCT07337408

• Monitoring diaphragm electrical activity and breathing effort during ventilator weaning

  We will see if surface diaphragm EMG, esophageal pressure, and oxygen use measured during a spontaneous breathing trial can predict who will fail to wean from the ventilator in the ICU.

  Recruiting Leiden University Medical Center · Leiden · NCT07109570

• Using levosimendan to shorten time on a ventilator

  This will test whether giving levosimendan to adults in the ICU who have failed a breathing trial helps them get off the ventilator sooner.

  Recruiting at 6 sites Phase 4 Radboud University Medical Center · Arnhem, Gelderland and 7 other locations · NCT07105202

• How differences in lung stiffness and breathing pressures affect getting off the ventilator after a tracheostomy

  This project will test whether measurements of regional lung compliance and transpulmonary driving pressure using electrical impedance tomography and esophageal pressure can explain why some tracheostomized patients on prolonged mechanical ventilation cannot be weaned.

  Recruiting National Taiwan University Hospital · Taipei · NCT07003672

• Impact of low phosphate levels on weaning off mechanical ventilation

  This study is testing if giving a phosphate supplement can help patients with low phosphate levels breathe better and get off mechanical ventilation more easily.

  Recruiting Peking Union Medical College · Beijing · NCT06754670

• Understanding factors related to weaning failure in critically ill patients on mechanical ventilation

  This study looks at why some critically ill patients on mechanical ventilation have trouble being taken off the ventilator, especially during their ICU stay.

  Recruiting Hospital Italiano de Buenos Aires · Buenos Aires · NCT06683781

• Improving respiratory muscle training for patients weaning off mechanical ventilation

  This study is testing different types of breathing exercises to see which helps patients coming off mechanical ventilation in the ICU breathe better and recover faster.

  Recruiting KU Leuven · Leuven · NCT04658498

Related topics

Quick answers

How many Weaning Failure clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in Netherlands (2 trials), Spain (1 trial), China (1 trial), Argentina (1 trial), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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