Characterization of weaning practices in ICUs in Global South countries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study conducted in ICUs in Global South countries. It includes adults on mechanical ventilation for at least 12 hours who plan extubation within the next 6 hours. Data are collected during the first 7 days after extubation, with follow-up until hospital discharge or death. The study aims to describe weaning practices and extubation outcomes across participating centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years.
* Receiving care at an intensive care unit.
* Endotracheal intubation.
* Mechanical ventilation for 12 hours or more.
* First separation attempt, as defined in the WIND Classification - "Separation attempt from mechanical ventilation: an spontaneous breathing trial with or without extubation, or an extubation directly performed without identified spontaneous breathing trial (whatever the type: planned or unplanned extubation)" - planned to occur in the next 6 hours or that occurred less than 2 hours ago.

Exclusion Criteria:

* Patients with prior extubation failure.
* Patients with prior spontaneous breathing trial failure.
* Patients unable to obey commands.
* Neuromuscular disease or cervical spinal cord injury.
* Tracheostomy.
* Do-not-resuscitate order or contraindication for reintubation.
* Lack of informed consent.
* Terminal extubation.
* Previously included in the study.

Where it's running

• Centro Hospitalar Unimed Joinville
  Joinville, Santa Catarina, Brazil Recruiting

Study contacts

• Study coordinator: Aline B Pereira
• Email: linibp@hotmail.com
• Phone: +55 (47) 99181-8400

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.