Condition

Spine Metastases clinical trials and research

• 12Clinical trials
• 2NIH research projects
• 4Countries

Newest Spine Metastases clinical trials

All recruiting trials (12)

• Heart-friendly medicines to protect chest-area cancer patients from radiation damage

  This Phase 2 trial tests whether taking atorvastatin and lisinopril can reduce heart damage in adults with chest-area cancers who receive radiation therapy.

  Recruiting Phase 2 UNC Lineberger Comprehensive Cancer Center · Chapel Hill, North Carolina · NCT07685938

• Spine tumor registry tracking outcomes after separation surgery and radiation

  This registry will collect information to see what outcomes adults with primary or metastatic spine tumors have after separation surgery followed by radiation.

  Recruiting at 5 sites Ohio State University Comprehensive Cancer Center · Indianapolis, Indiana and 4 other locations · NCT07225491

• Radiofrequency ablation and bone augmentation plus radiotherapy vs radiotherapy alone for spinal metastases

  This trial will test whether adding radiofrequency ablation and bone augmentation to radiotherapy helps people with metastatic spine disease (T5-L5) have fewer skeletal-related events and less pain.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07090122

• Evaluating radiofrequency ablation and stabilization for metastatic spine lesions

  This study is testing if a new treatment that combines radiofrequency ablation and stabilization can help people with certain types of spine tumors feel better by looking at changes in their lesions after treatment.

  Recruiting National and Kapodistrian University of Athens · Athens, Athens · NCT06716294

• Radiation treatment for high-risk spine cancer patients

  This study is testing a new type of radiation treatment for patients with cancer that has spread to the spine to see if it can help manage their condition without needing major surgery.

  Recruiting Phase 2 Stony Brook University · Stony Brook, New York · NCT06165419

• Radiotherapy for patients with minimally symptomatic spinal metastases

  This study tests whether giving early radiation therapy to patients with mild spinal metastases can help prevent serious bone problems and improve their overall health.

  Recruiting Phase 1/2 Baptist Health South Florida · Miami, Florida · NCT05534321

• Treatment for limited spine metastases after surgery

  This study is testing whether a new type of targeted radiation therapy works better than regular radiation for people who have had surgery for limited spine cancer that has spread from other solid tumors.

  Recruiting National Taiwan University Hospital · Taipei · NCT05495399

• Combining vertebroplasty with radiation therapy for spine metastases pain relief

  This study is testing whether combining a procedure to strengthen the spine with radiation therapy can help people with spine cancer feel less pain and lower their chances of fractures.

  Recruiting at 2 sites Centre hospitalier de l'Université de Montréal (CHUM) · Montreal, Quebec and 1 other locations · NCT05317026

• Combining laser treatment and radiosurgery for spinal tumors

  This study is testing if using both laser treatment and targeted radiation can help people with spinal tumors feel better and improve their quality of life compared to just using radiation alone.

  Recruiting Henry Ford Health System · Detroit, Michigan · NCT05023772

• New approach to treat localized spine metastases with radiation therapy

  This study is testing a new way to use radiation therapy over five sessions to see if it can help people with spine metastases manage pain better and improve their overall function.

  Recruiting Baptist Health South Florida · Miami, Florida · NCT04802603

• Comparing single and double sessions of spine radiosurgery for vertebral metastases

  This study is testing whether one or two sessions of targeted radiation therapy can better help people with cancer spread to the spine by reducing the risk of fractures and improving their overall well-being.

  Recruiting Phase 2 Case Comprehensive Cancer Center · Cleveland, Ohio · NCT04218617

• Using MRI to guide radiation therapy for various cancers

  This study is testing if using MRI scans to adjust radiation therapy can help people with different types of cancer, like pancreatic and lung cancer, feel better and control their tumors more effectively.

  Recruiting at 2 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT04115254

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Stem cell drivers of breast cancer spine metastases

  Scientists are studying how a special bone-forming cell in the spine helps breast cancer spread to the spine, with the goal of stopping or slowing that spread.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11364133

• Understanding how a special stem cell helps breast cancer spread to the spine

  This research aims to understand why breast cancer often spreads to the spine by looking at a newly found type of stem cell in the vertebrae.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11051822

Related topics

Quick answers

How many Spine Metastases clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (9 trials), Canada (1 trial), Taiwan (1 trial), Greece (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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