Condition

SLE clinical trials and research

• 10Clinical trials
• 1New in 30 days
• 13Countries

Newest SLE clinical trials

All recruiting trials (10)

• Predicting SLE Flares with Patient Reports and Machine Learning

  Aims to test a low-cost, patient-reported outcome–based machine learning tool to see if it can detect lupus flares early and support care, especially in settings with limited resources.

  Recruiting Sohag University · Sohag, Nasr City · NCT07890662

• Anti-CD19/BCMA universal CAR-T (RD06-05) for autoimmune diseases

  This early-phase test gives a universal CAR-T therapy (RD06-05) that targets CD19 and BCMA to adults with autoimmune diseases such as SLE/lupus nephritis, ANCA-associated vasculitis, and anti-GBM disease.

  Recruiting Early Phase 1 Nanjing Bioheng Biotech Co., Ltd. · Shanghai, Shanghai Municipality · NCT07203404

• Pregnancies before a lupus diagnosis

  See if pregnancies that happened before women were diagnosed with lupus showed early lupus signs and how those pregnancies affected mothers and babies.

  Recruiting University of Algiers · Aïn Taya, Algiers Province and 1 other locations · NCT07148115

• ONT01 for Lupus Nephritis and Systemic Lupus Erythematosus

  We will test whether ONT01 is safe and helps adults with lupus nephritis or active SLE when added to standard medicines like mycophenolate.

  Recruiting Early Phase 1 Hospital for Special Surgery, New York · New York, New York · NCT07107659

• CART19 treatment for lupus in young patients

  This study is testing a new treatment called CART19 to see if it can help young people aged 12-29 with tough-to-treat lupus feel better and improve their health.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06839976

• Targeted CAR-T therapy for autoimmune diseases

  This study is testing a new CAR-T cell therapy to see if it can help people with autoimmune diseases like lupus, scleroderma, and multiple sclerosis feel better.

  Recruiting Early Phase 1 Nanjing Bioheng Biotech Co., Ltd. · Lianyungang, Jiangus · NCT06775912

• Cell therapy using UC-MSCs for patients with lupus

  This study is testing if a new treatment using stem cells from umbilical cords can help adults with lupus feel better and improve their kidney health.

  Recruiting Phase 1 LiveKidney.Bio · Charleston, South Carolina · NCT06737380

• Using CLN-978 to treat patients with systemic lupus erythematosus

  This study is testing a new treatment called CLN-978 to see if it can help people with moderate to severe lupus who haven't responded well to other treatments.

  Recruiting at 22 sites Phase 1 Cullinan Therapeutics Inc. · Avondale, Arizona and 23 other locations · NCT06613360

• Evaluating APG-2575 for mild-to-moderate lupus

  This study is testing a new drug called APG-2575 to see if it is safe and effective for people with mild-to-moderate lupus.

  Recruiting Phase 1/2 Ascentage Pharma Group Inc. · Shanghai, Shanghai Municipality · NCT06182969

• Registry of Argentinian patients with lupus

  This study is gathering information from Argentinian patients with lupus over five years to better understand their experiences, treatments, and health outcomes.

  Recruiting Sociedad Argentina de Reumatologia · La Plata, Buenos Aires · NCT05470569

Related topics

Quick answers

How many SLE clinical trials are recruiting right now?

10, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (4 trials), China (3 trials), Australia (1 trial), Bulgaria (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 3, Phase 1: 2, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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