Condition

NMOSD clinical trials and research

• 7Clinical trials
• 13Countries

Newest NMOSD clinical trials

All recruiting trials (7)

• Ravulizumab in Chinese adults with NMOSD

  This study tests ravulizumab in Chinese adults with NMOSD who are AQP4 antibody positive to see if it helps reduce relapses and is safe.

  Recruiting Phase 3 Alexion Pharmaceuticals, Inc. · Beijing and 9 other locations · NCT07557420

• Transcranial alternating current stimulation for cognitive problems in inflammatory demyelinating CNS disorders

  This trial will try transcranial alternating current stimulation to see if it improves thinking and memory in adults with multiple sclerosis and related inflammatory demyelinating central nervous system disorders.

  Recruiting Xuanwu Hospital, Beijing · Beijing, Beijing Municipality · NCT07087873

• Rituximab vs multiple approved NMOSD therapies to prevent relapses

  This study tests whether rituximab or one of four other approved medicines is better at preventing NMOSD relapses in adults who have AQP4-IgG.

  Recruiting at 2 sites Phase 4 Massachusetts General Hospital · Boston, Massachusetts and 2 other locations · NCT07010302

• Pregnancy registry for women with chronic neurological conditions

  This study is collecting information and samples from pregnant women with chronic neurological conditions to see how pregnancy affects their health and their baby's development.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06940323

• Targeted CAR-T therapy for autoimmune diseases

  This study is testing a new CAR-T cell therapy to see if it can help people with autoimmune diseases like lupus, scleroderma, and multiple sclerosis feel better.

  Recruiting Early Phase 1 Nanjing Bioheng Biotech Co., Ltd. · Lianyungang, Jiangus · NCT06775912

• Registry of patients with AQP4+ NMOSD treated with C5 inhibitors

  This study is collecting information from people with AQP4+ NMOSD who are being treated with C5 inhibitors to see how well these treatments work and how they affect daily life over five years.

  Recruiting at 23 sites Alexion Pharmaceuticals, Inc. · Washington D.C., District of Columbia and 32 other locations · NCT05966467

• Evaluating satralizumab for children with neuromyelitis optica spectrum disorder

  This study is testing a new treatment called satralizumab to see if it helps children aged 2 to 11 with neuromyelitis optica spectrum disorder feel better and stay safe.

  Recruiting at 13 sites Phase 3 Hoffmann-La Roche · Denver, Colorado and 13 other locations · NCT05199688

Related topics

Quick answers

How many NMOSD clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in China (5 trials), United States (4 trials), Argentina (2 trials), Italy (2 trials), Germany (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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