Pregnancies before a lupus diagnosis
Official title: Pregnancy Outcomes Prior to a Systemic Lupus Erythematosus Diagnosis
Run by University of Algiers · NCT07148115 · Data updated 2026-11-12
See if pregnancies that happened before women were diagnosed with lupus showed early lupus signs and how those pregnancies affected mothers and babies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 55 Years |
| Sex | Women only |
| Enrollment | 50 (estimated) |
| Sponsor | University of Algiers Academic / other |
| Locations | 2 sites (Aïn Taya, Algiers Province and 1 other locations) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | December 31, 2025 |
| Study ends | April 30, 2026 |
| Registry record updated | December 31, 2025 |
| Trial ID | NCT07148115 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women diagnosed with SLE after at least one pregnancy, who meet ACR 1997 or EULAR 2019 criteria and can provide access to their pregnancy medical records and attend the Ain-Taya clinic, are the intended participants.
✕Probably not a fit
Women diagnosed with SLE before any conception, those without accessible pregnancy records, or those unable to attend the Ain-Taya site are unlikely to receive benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective, single-center cohort using medical record review and brief participant interviews to collect obstetrical and systemic data from pregnancies that occurred before a later diagnosis of systemic lupus erythematosus (SLE). Investigators will include women classified as having SLE by ACR 1997 or EULAR 2019 criteria and extract details on each pregnancy, maternal and fetal outcomes, and any systemic or obstetrical signs noted during or before pregnancy. The analysis will describe the presence of prediagnostic systemic signs, report pregnancy outcomes (for example miscarriage, preterm birth, fetal loss), and summarize SLE severity after diagnosis. Results aim to identify patterns that might signal undiagnosed SLE during pregnancy and inform future monitoring and counseling.
Why it matters
Potential benefit: If successful, the findings could help clinicians spot early SLE signs during pregnancy and improve monitoring and counseling for affected mothers and future pregnancies.
How similar studies have gone: Previous retrospective cohorts have suggested obstetrical complications and prediagnostic systemic signs can precede SLE diagnosis, but published data are limited and not definitive.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Women of childbearing age with a history of at least one pregnancy * Pregnancy occurred before the diagnosis of LES. * LES was diagnosed after at least one pregnancy. * The subject is classified as having LES according to the 1997 ACR or EULAR 2019 criteria. Exclusion criteria: LES was previously diagnosed prior to any conception.
Where it's running
-
Ain-Taya's Public Hospital
Algiers, Algeria Recruiting -
Department of internal medicine, Ain-Taya's teaching Public hospital
Aïn Taya, Algiers Province, Algeria Active not recruiting
Study contacts
- Study coordinator: Wafia- Nadia Nibouche - Hattab, Professor in medicine
- Email: wani16000@yahoo.fr
- Phone: +213-771-810-932
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.