Clinical trial Recruiting at 1 site Observational Ages 18 and up

Radiotherapy for Head and Neck Cancer with Simultaneous Integrated Boost

Official title: Simultaneous Integrated Boost in the Primary and Adjuvant Therapy of Head and Neck Cancer: Quality Control Registry Prospective Longitudinal Obervation Trial

Run by Wuerzburg University Hospital · NCT06831903 · Data updated 2026-11-12

This study is testing a new type of radiation therapy for people with head and neck cancer to see if it helps them live longer and feel better while causing fewer side effects.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment750 (estimated)
SponsorWuerzburg University Hospital
Academic / other
Drugs / interventionsradiation
Locations1 site (Würzburg, Bavaria)
StatusRecruiting
StartedMay 21, 2019
Main results expectedOctober 1, 2034
Study endsOctober 1, 2039
Registry record updatedFebruary 18, 2025
Trial IDNCT06831903 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with histologically confirmed malignant head and neck tumors who are undergoing definitive or adjuvant radio(chemo)therapy.

Probably not a fit

Patients with basal cell carcinoma or those unable to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the efficacy and safety of simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) in patients with head and neck cancers. It aims to assess local and regional control, overall survival, metastasis-free survival, and therapy-related toxicities while documenting patient-reported quality of life. The study follows a prospective, longitudinal design, collecting real-world outcomes and quality measures in accordance with clinical guidelines. Patients with confirmed malignancies will receive individualized treatment plans designed to minimize toxicity while effectively targeting high-risk tumor areas.

Why it matters

Potential benefit: If successful, this study could improve treatment outcomes and quality of life for patients with head and neck cancers.

How similar studies have gone: Other studies utilizing similar SIB techniques have shown promising results, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18 and older with histologically confirmed malignant head and neck tumors, undergoing definitive or adjuvant radio(chemo)therapy at the University Hospital Würzburg

Exclusion Criteria:

* missing informed consent
* mental or physical disorders leading to inability to understand and/or fill the quationary
* judgment by the investigator that the participant should not participate in the study if the participant is unlikely to comply with study procedures

Where it's running

  • University Clinic of Wuerzburg
    Würzburg, Bavaria, Germany
    Recruiting

Study contacts

  • Principal investigator: Victor Lewitzki, MD, PhD — University Clinic of Wuerzburg, Department of Radiation Oncology
  • Study coordinator: Victor Lewitzki, MD, PhD
  • Email: lewitzki_v@ukw.de
  • Phone: +49-931-201-28869

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.