Condition

Psychological Stress clinical trials and research

• 13Clinical trials
• 6NIH research projects
• 6Countries

Newest Psychological Stress clinical trials

All recruiting trials (13)

• Presurgical Diagram Illustration and Stress in Wisdom Tooth Surgery

  This study tests whether showing patients a diagram of the wisdom tooth surgery before the procedure affects their stress levels.

  Recruiting Delta University for Science and Technology · Al Mansurah, Addakahlyia · NCT07803510

• Sleep More, Stress Less with Neuralli Mood

  This 90-day, open-label study tests whether daily Neuralli Mood capsules can help adults feel less stressed, sleep better, and improve mood and burnout symptoms.

  Recruiting Efforia, Inc · New York, New York · NCT07717385

• Ashwagandha for stress, anxiety, and sleep in sexual and gender minority adults

  This 8-week test will see if taking Ashwagandha root extract twice daily can reduce stress and anxiety and improve sleep in sexual and gender minority adults aged 18–45 who report moderate to high perceived stress.

  Recruiting SF Research Institute, Inc. · San Francisco, California · NCT07441070

• Stappvoorstap: support for adults waiting for mental healthcare

  This project will test whether the Stappvoorstap mobile app can reduce stress and improve coping and quality of life for adults on mental health waiting lists in the Netherlands.

  Recruiting GGZ Centraal · Almere Stad, Flevoland · NCT07391072

• How Stress and Social Context May Influence Alcohol Choices

  We’re testing whether acute stress and being with others affect whether people choose an alcoholic drink over a non-alcoholic one.

  Recruiting University of Washington · Seattle, Washington · NCT07390084

• Psilocybin-assisted therapy for adults who are biological children of genocide survivors

  This project will test whether two supervised 25 mg doses of psilocybin plus preparation and integration therapy help adults who are biological children of genocide survivors reduce depression, anxiety, and stress.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT06899165

• Examining trauma and health in an American Indian community

  This study is trying to see how past trauma affects the health of American Indian volunteers by looking at their blood, body composition, and responses to stress.

  Recruiting Montana State University · Browning, Montana · NCT06878885

• Effects of aerobic exercise with music on medical students' mental health

  This study tests if an 8-week aerobic exercise program with music can help medical students in China feel less stressed and improve their focus and thinking skills.

  Recruiting Universiti Sains Malaysia · Yancheng, Jiangsu · NCT06788106

• Examining how psychological stress affects heart and brain health in midlife adults

  This study tests how psychological stress affects heart and brain health in midlife adults by looking at their cardiovascular responses and brain scans in a lab setting.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06029348

• Exploring how psychological stress affects lung cancer treatment outcomes

  This study is trying to see how psychological stress affects the success of immune treatments for different types of lung cancer patients.

  Recruiting Second Xiangya Hospital of Central South University · Changsha, Hunan · NCT05477979

• An internet-based compassion course for healthcare professionals

  This study is testing an online compassion course to see if it can help healthcare workers feel less stressed and improve their job satisfaction.

  Recruiting Linnaeus University · Vaxjo, Kronoberg County · NCT04700878

• Impact of COVID-19 on Alcohol Use and Related Issues

  This study is looking to see how the COVID-19 pandemic has changed drinking habits and related issues for people, especially those with alcohol use problems, over a couple of years.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04391816

• Understanding health trends in Puerto Rico

  This study is trying to understand health trends in Puerto Rico by looking at diet, mental health, and heart health in adults aged 30-75 over time.

  Recruiting Harvard School of Public Health (HSPH) · San Juan · NCT03794531

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Role of epithelial ROS signaling in stress-related gut dysfunction and colitis risk

  This NIH grant looks at how stress changes the gut lining and its microbes, possibly increasing the risk of inflammatory bowel disease in people who are genetically predisposed.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11361588

• Understanding how stress affects young people

  This project explores how stress affects young male and female mice to better understand why depression often starts in adolescence and affects girls more than boys.

  NIH research University of Texas El Paso · El Paso, United States · NIH-11105909

• Understanding how stress affects gut health and IBD risk

  This project explores how psychological stress changes the gut lining and bacteria, which might make some people more likely to develop inflammatory bowel diseases.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11092247

• How brain stimulation affects emotional responses to stress

  This study is looking at how short-term stress affects our feelings and body responses, and it’s for adults who want to understand how brain stimulation can change how we react to stress.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10948563

• Investigating how psychological stress affects young male and female mice

  This study looks at how stress affects young male and female mice and how it might lead to feelings similar to depression, helping us understand the differences in how boys and girls handle stress during their growing years.

  NIH research University of Texas El Paso · El Paso, United States · NIH-10874565

• A system to automatically manage blood sugar levels during unexpected activities and stress.

  This study is working on a smart insulin delivery system that automatically adjusts your insulin based on real-time information about your blood sugar, especially when you’re active or feeling stressed, to help make managing diabetes easier and keep you safer.

  NIH research Illinois Institute of Technology · Chicago, United States · NIH-10488195

Related topics

Quick answers

How many Psychological Stress clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (7 trials), China (2 trials), Egypt (1 trial), Puerto Rico (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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