Investigating how psychological stress affects young male and female mice
Psychological stress susceptibility in juvenile female and male mice
This study looks at how stress affects young male and female mice and how it might lead to feelings similar to depression, helping us understand the differences in how boys and girls handle stress during their growing years.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas El Paso NIH-funded |
| Lab location | 1 site (El Paso, United States) |
| Project ID | NIH-10874565 on NIH RePORTER |
What this research studies
This research explores the impact of psychological stress on juvenile male and female mice, focusing on how these experiences may lead to symptoms similar to major depressive disorder (MDD). The study utilizes a unique method where a mouse observes another mouse being defeated, which mimics stress-related behaviors. By including both genders and younger mice, the research aims to uncover the neurobiological factors contributing to mood disorders during critical developmental stages. The findings could provide insights into the differences in how stress affects males and females, particularly during adolescence.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be adolescents experiencing mood-related issues or those at risk for developing such conditions.
Not a fit: Patients who are not adolescents or those without mood-related disorders may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for mood disorders in adolescents.
How similar studies have performed: Previous research has shown success in using similar animal models to study mood disorders, although this specific approach focusing on juvenile populations is relatively novel.
Where this research is happening
El Paso, United States
- University of Texas El Paso — El Paso, United States (Active)
Researchers
- Principal investigator: Iniguez, Sergio Diaz — University of Texas El Paso
- Study coordinator: Iniguez, Sergio Diaz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.