Clinical trial Recruiting at 1 site Interventional Ages 18 to 32

Presurgical Diagram Illustration and Stress in Wisdom Tooth Surgery

Official title: Role of Presurgical Illustration on Patients' Psychological Stress Monitored by Salivary Cortisol in Mandibular Third Molar Surgery

Run by Delta University for Science and Technology · NCT07803510 · Data updated 2026-11-12

This study tests whether showing patients a diagram of the wisdom tooth surgery before the procedure affects their stress levels.

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Quick facts

Study typeInterventional
Ages18 Years to 32 Years
SexAll
Enrollment80 (estimated)
SponsorDelta University for Science and Technology
Academic / other
Locations1 site (Al Mansurah, Addakahlyia)
StatusRecruiting
StartedSeptember 5, 2026
Main results expectedNovember 2026
Study endsNovember 2026
Registry record updatedSeptember 9, 2026
Trial IDNCT07803510 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy adults (ASA I) needing mandibular third molar extraction with the specified surgical steps and who consent to saliva sampling.

Probably not a fit

Patients with acute dental pain, active oral pathologies, psychiatric conditions, or factors affecting cortisol or saliva secretion may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial investigates how a presurgical diagrammatic explanation of mandibular third molar extraction influences psychological stress, measured in part by saliva cortisol. Healthy adults requiring extraction with specific surgical steps are enrolled, and presurgical illustrations are provided as the intervention. Saliva samples are collected before and after surgery to assess stress changes. The study uses an interventional design to gauge whether orientation with visuals reduces or increases fear and anxiety related to the procedure.

Why it matters

Potential benefit: If successful, the approach could reduce preoperative stress and improve patient experience during wisdom tooth surgery.

How similar studies have gone: Previous work suggests that medical illustrations can influence patient anxiety, but evidence specific to presurgical diagrams in third-molar surgery is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy patients (American Society of Anesthesiologists Class I),
* Patients demanding extraction of their mandibular third molar,
* Mandibular third molars requiring flap raising, bone removal, coronal and radicular sectioning (Modified Parant Scale Class IV),
* Patients accepting their saliva sampling prior to and after surgery.

Exclusion Criteria:

* Acutely painful mandibular third molars on clinical examination,
* Pericoronal and/or active periapical and/or active periodontal pathologies on clinical and radiographic examinations,
* Patients using steroids,
* Psychiatric patients,
* Smokers,
* Pregnant patients, and/or those observing their menstruation,
* Patients with conditions of altered cortisol secretion (such as Addison's disease, Cushing's syndrome, and congenital adrenal hyperplasia),
* Patients with altered secretion of saliva (such as due to using atropine, calcium channel blockers, antidepressants, antihistamines, Sjogren's syndrome, and radiotherapy).
* Patients who are overtly anxious about dental treatment (scoring \>19 on the Modified Dental Anxiety Scale).

Where it's running

  • Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology
    Al Mansurah, Addakahlyia, Egypt
    Recruiting

Study contacts

  • Principal investigator: Mohammad Abdelhamid, PhD — Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology
  • Study coordinator: Mohammad Abdelhamid, PhD
  • Email: hamidsurgeon@gmail.com
  • Phone: 00201002285659

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.