Condition

Borderline Resectable Pancreatic Adenocarcinoma clinical trials and research

• 8Clinical trials
• 6Countries

Newest Borderline Resectable Pancreatic Adenocarcinoma clinical trials

All recruiting trials (8)

• HRS-4642 plus nimotuzumab and chemotherapy for borderline resectable pancreatic cancer with KRAS G12D

  This Phase II trial will test whether adding HRS-4642 and nimotuzumab to gemcitabine and albumin-bound paclitaxel helps adults with borderline resectable pancreatic cancer that has a KRAS G12D mutation.

  Recruiting Phase 2 Zhejiang University · Hangzhou, Zhejiang and 1 other locations · NCT07240766

• ctDNA MRD monitoring during neoadjuvant treatment for pancreatic cancer

  We will see if regular blood tests for ctDNA (MRD) during neoadjuvant therapy can predict surgical success and longer survival for adults with borderline resectable or high‑risk resectable pancreatic cancer.

  Recruiting at 2 sites Ruijin Hospital · Shanghai and 1 other locations · NCT07080021

• PTM-101 treatment for pancreatic cancer

  This study is testing a new treatment called PTM-101 combined with chemotherapy to see if it can help people with certain types of pancreatic cancer who haven't had treatment before.

  Recruiting at 9 sites Phase 1 PanTher Therapeutics · Newport Beach, California and 8 other locations · NCT06673017

• Neoadjuvant treatment for borderline resectable pancreatic cancer

  This study is testing a new combination of chemotherapy, immunotherapy, and radiation before surgery to see if it can help people with borderline resectable pancreatic cancer live longer and have better treatment results.

  Recruiting at 3 sites Phase 1/2 Amsterdam UMC, location VUmc · Amsterdam and 3 other locations · NCT06384560

• Chemotherapy sequence for pancreatic cancer treatment

  This study is testing a new order of chemotherapy drugs to see if it helps people with hard-to-treat pancreatic cancer have their tumors completely removed through surgery.

  Recruiting at 2 sites Phase 2 Wake Forest University Health Sciences · Charlotte, North Carolina and 1 other locations · NCT05825066

• Combining zimberelimab and quemliclustat with chemotherapy for advanced pancreatic cancer

  This study is testing if a new combination of zimberelimab and quemliclustat with chemotherapy can help people with advanced pancreatic cancer live longer and have better treatment outcomes.

  Recruiting Phase 1/2 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT05688215

• Assessing survival and quality of life in patients with advanced pancreatic cancer

  This study looks at how long people with advanced pancreatic cancer live and how their quality of life is affected while being treated at different hospitals in the Nordic region.

  Recruiting Umeå University · Umeå · NCT05356039

• Preoperative chemotherapy with radiation for borderline resectable pancreatic cancer

  This study is testing whether adding a specific type of radiation therapy to chemotherapy before surgery can help people with borderline resectable pancreatic cancer have better outcomes.

  Recruiting at 9 sites Phase 2 Erasme University Hospital · Antwerp and 9 other locations · NCT05083247

Related topics

Quick answers

How many Borderline Resectable Pancreatic Adenocarcinoma clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), China (2 trials), Belgium (1 trial), Australia (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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