Using technology to improve care for pancreatic cancer patients
Official title: Improving Pancreatic Cancer Care by the Use of Computational Science and Technology
Run by UMC Utrecht · NCT06055010 · Data updated 2026-11-12
This study is trying to see if sharing patient data among hospitals can help improve care and outcomes for people with pancreatic cancer.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | UMC Utrecht Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Utrecht) |
| Status | Recruiting |
| Started | January 1, 2014 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | September 26, 2023 |
| Trial ID | NCT06055010 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who have received diagnostic procedures or treatment for pancreatic lesions.
✕Probably not a fit
Patients who object to the use of their data for scientific research will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The IMPACT project aims to establish a data-sharing infrastructure among expert centers for pancreatic surgery to enhance the quality of care for patients with pancreatic cancer. This observational study will collect pseudonymized clinical and imaging data from patients who have undergone diagnostic procedures and treatments for pancreatic lesions. The data will be utilized to train and validate artificial intelligence tools that can potentially improve patient outcomes. A project steering committee will oversee the management and sharing of the collected data among participating centers.
Why it matters
Potential benefit: If successful, this project could lead to improved diagnostic and treatment strategies for pancreatic cancer patients.
How similar studies have gone: Other studies utilizing data-sharing and artificial intelligence in oncology have shown promising results, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥18 years of age * Patients who received diagnostic procedures and/or treatment for (suspected) benign and malignant pancreatic lesions as registered in the Dutch Pancreatic Cancer Project (PACAP) audit database and healthy individuals who received an abdominal CT-scan (controls) Exclusion Criteria: \- Subjects who object to the use of their data for the purpose of scientific research
Where it's running
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Regional Academic Cancer Center Utrecht
Utrecht, Netherlands Recruiting
Study contacts
- Study coordinator: Lois A Daamen, MD, PhD
- Email: l.a.daamen-3@umcutrecht.nl
- Phone: +31651223276
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Developing a blood test for early diagnosis of pancreatic cancer
This study is trying to develop a simple blood test to help find pancreatic cancer early and track how well treatments are working for patients.
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Zoldonrasib plus Daraxonrasib vs Gemcitabine and Nab-Paclitaxel as first-line treatment for metastatic KRAS G12D pancreatic cancer
This study tests whether two investigational RAS inhibitors together can improve outcomes compared with standard chemotherapy in adults with newly diagnosed metastatic pancreatic cancer carrying the KRAS G12D mutation.
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Liquid biopsy biomarkers to detect and monitor pancreatic cancer
Researchers test blood-based microRNA signals to see if they can identify pancreatic cancer risk or early disease in people with familial or hereditary risk or mucinous cysts.
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Zoldonrasib + chemotherapy vs placebo + chemotherapy as first-line treatment for metastatic KRAS G12D pancreatic cancer
This trial tests whether adding zoldonrasib to standard chemotherapy helps people with newly diagnosed metastatic KRAS G12D pancreatic cancer.
-
Atebimetinib plus gemcitabine and nab‑paclitaxel as first‑line treatment for metastatic pancreatic cancer
This trial will test whether adding the MAPK pathway drug atebimetinib to gemcitabine and nab‑paclitaxel helps people with newly diagnosed metastatic pancreatic ductal adenocarcinoma live longer.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.