Condition
Pain After Surgery clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Pain After Surgery clinical trials that are recruiting, at sites in 3 countries (most in United States (4), China (2), Turkey (Türkiye) (1)). By phase: Phase 4 (2), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 3Countries
Newest Pain After Surgery clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| See if virtual reality headsets can help with pain and anxiety after open-heart surgery | — | Izmir | Recruiting | Sep 28, 2026 |
| Pain relief after abdominal surgery: testing HSK55718 against morphine and placebo | Phase 2 | Changsha, Hunan and 1 other locations | Recruiting | Apr 16, 2026 |
| Post-Operative Pain Relief with Zynrelef vs Periarticular Injections in Robot-Assisted Knee Replacement | Phase 4 | Cranberry Township, Pennsylvania | Recruiting | Feb 24, 2026 |
| Virtual reality to reduce pain and anxiety during first-trimester procedural abortion | — | Pittsburgh, Pennsylvania and 1 other locations | Recruiting | Dec 17, 2025 |
| Tegileridine for postoperative pain after adolescent scoliosis surgery | Phase 4 | Zhengzhou, Henan and 5 other locations | Recruiting | Nov 17, 2025 |
| Lowering opioid use before spine surgery | — | Philadephia, Pennsylvania | Recruiting | Oct 28, 2025 |
| Mindfulness to support recovery after colorectal surgery | — | Cleveland, Ohio | Recruiting | Jun 18, 2025 |
All recruiting trials (7)
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See if virtual reality headsets can help with pain and anxiety after open-heart surgery
This randomized trial tests whether using virtual reality headsets after open-heart surgery reduces pain and anxiety and improves satisfaction and physiological measures compared with standard care.
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Pain relief after abdominal surgery: testing HSK55718 against morphine and placebo
We’re testing whether HSK55718 can safely and effectively reduce pain after abdominal surgery, compared with morphine and a placebo.
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Post-Operative Pain Relief with Zynrelef vs Periarticular Injections in Robot-Assisted Knee Replacement
This study tests whether the Zynrelef extended-release periarticular injection can reduce pain and opioid use after robot-assisted total knee arthroplasty compared with standard periarticular injections.
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Virtual reality to reduce pain and anxiety during first-trimester procedural abortion
This trial will test whether wearing a VR headset that shows a meditative nature video during a first-trimester procedural abortion reduces pain and anxiety and increases satisfaction compared with usual care.
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Tegileridine for postoperative pain after adolescent scoliosis surgery
This trial tests whether Tegileridine can provide pain relief after spine surgery in teens as well as morphine, using a patient-controlled pump and comparing safety profiles.
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Lowering opioid use before spine surgery
This pilot test tries two tapering approaches for adults who take daily opioids and have spine surgery scheduled at least four weeks away—education alone versus education plus two CBT sessions—to see which helps them reduce opioids by the time of surgery.
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Mindfulness to support recovery after colorectal surgery
This study will try teaching adults having colorectal surgery simple mindfulness exercises to help them feel calmer and manage pain after surgery.
Related topics
Quick answers
How many Pain After Surgery clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (4 trials), China (2 trials), Turkey (Türkiye) (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.