Mindfulness to support recovery after colorectal surgery

Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery: A Single Center RCT Feasibility Study

Not applicable Interventional University Hospitals Cleveland Medical Center · NCT07026786

This study will try teaching adults having colorectal surgery simple mindfulness exercises to help them feel calmer and manage pain after surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospitals Cleveland Medical Center Academic / other
Locations1 site (Cleveland, Ohio)
Trial IDNCT07026786 on ClinicalTrials.gov

What this trial studies

Participants having colorectal bowel resection and enrolled in the hospital's ERAS pathway will be randomly assigned to a mindfulness intervention or to standard treatment. Those in the mindfulness arm receive a 30-minute preoperative Zoom session teaching simple exercises (deep breathing, sensory grounding, present-moment focus) and watch a short review video the day after surgery. All participants complete questionnaires about pain, anxiety, and medication use, and a subset will do a semi-structured Zoom interview 2 weeks to 1 month after surgery. Investigators will also collect demographic and surgical details and track postoperative pain scores and opioid consumption, and access to the mindfulness curriculum will be provided to those not originally randomized to it.

Who should consider this trial

Good fit: Adults (18+) scheduled for bowel resection enrolled in the University Hospitals ERAS pathway who will stay at least one night in the hospital, speak English, and have internet access for Zoom are ideal candidates.

Not a fit: Patients having only same-day discharge, undergoing palliative or ostomy take-down procedures, those with active substance use disorder, severe sensory or cognitive impairment, no internet access, or insufficient English proficiency are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the intervention could help reduce postoperative anxiety and pain and may lower the need for opioid pain medication.

How similar studies have performed: Mindfulness interventions have shown some benefit for anxiety and pain in surgical and pain-management settings, but integrating mindfulness into an ERAS protocol for colorectal surgery is relatively novel and not widely tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients scheduled for a bowel resection and enrolled in the UH Institutional ERAS pathway
* Patients will be admitted to the inpatient hospital for at least one day postoperatively
* Aged 18 or older
* Receiving surgery at designated University Hospitals locations (Cleveland Medical Center, Ahuja, St. John's Medical Center)
* English-speaking
* Access to the internet via phone, laptop, or iPad

Exclusion Criteria:

* Surgery for palliative purposes only
* Surgery for ostomy take-down only
* Discharged on day of surgery
* History of substance use disorder
* Allergy or intolerance to all opioids
* Insufficient English proficiency
* No access to the internet outside clinical settings
* Significant visual, hearing or cognitive impairment

Where this trial is running

Cleveland, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pain After SurgeryAnxiety After SurgeryColorectal surgery patientsMindfulnessEnhanced Recovery After Surgery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.