Lowering opioid use before spine surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized pilot will enroll 45 adults taking 40–200 oral morphine milligram equivalents daily who are scheduled for major spine surgery at least four weeks in advance. Participants are assigned to personalized opioid tapering with education alone or to the same tapering plus two preoperative cognitive behavioral therapy (CBT) sessions, with pain physicians designing individual taper plans. Pain, opioid withdrawal, depression, and anxiety are monitored during the month prior to surgery and throughout hospitalization, and opioid use at the time of surgery is the primary outcome. Additional hospital outcomes, including postoperative pain, opioid requirements, complications, and length of stay, will also be recorded.

Why it matters

Who can join: the full rules

Inclusion:

* at least 18 years old
* scheduled for major spine surgery (i.e. at least 1 level of fusion) with hospital admission of at least one night
* scheduled for spine surgery at least 4 weeks ahead of time
* takes between 40 and 200 oral morphine equivalents daily

Exclusion:

* inability to use a computer or tablet for telemedicine encounters
* non-English-speaking
* inability to complete assessments
* positive screen on the Columbia Suicide Screening Assessment

Where it's running

• Thomas Jefferson University Hospital
  Philadephia, Pennsylvania, United States Recruiting

Study contacts

• Study coordinator: Eric Schwenk, MD
• Email: eric.schwenk@jefferson.edu
• Phone: 267-239-3319

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.