Condition

Open Angle Glaucoma (OAG) clinical trials and research

• 11Clinical trials
• 5Countries

Newest Open Angle Glaucoma (OAG) clinical trials

All recruiting trials (11)

• Eye drops Rhopressa vs Timolol to protect nerve cells in glaucoma

  In adults with open-angle glaucoma, this study tests whether Rhopressa helps preserve retinal nerve cells better than Timolol while both lower eye pressure.

  Recruiting Phase 4 Indiana University · Bloomington, Indiana · NCT07847073

• iDose TR implant administration in an office-based eye clinic

  This study tests a travoprost implant (iDose TR) given inside the eye to people with open-angle glaucoma or high eye pressure in an office setting to see if it is safe.

  Recruiting Glaukos Corporation · Austin, Texas · NCT07816692

• Brillouin hydration mapping to study cornea health

  Researchers test a Brillouin microscope to see if it can measure corneal water content in healthy people and those with eye conditions.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07780890

• Direct (non-contact) laser versus standard selective laser for treating glaucoma

  This test compares a newer non-contact laser (DSLT) with the standard SLT to see if it lowers eye pressure just as well in adults with open-angle glaucoma or ocular hypertension.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT07408154

• Updated inserter for the 75 mcg Travoprost intracameral implant

  This study will see if the new G2-TRIO inserter reliably and safely delivers the 75 mcg Travoprost intracameral implant in adults with open-angle glaucoma or ocular hypertension.

  Recruiting Glaukos Corporation · Kenosha, Wisconsin · NCT07400926

• Cataract surgery with iStent inject versus Kahook Dual Blade goniotomy for open-angle glaucoma

  This trial tests whether adding either two iStent inject implants or a Kahook Dual Blade goniotomy at the time of cataract surgery helps people with open-angle glaucoma lower eye pressure or reduce glaucoma medications.

  Recruiting at 2 sites Medical University of Bialystok · Bialystok, Polska and 1 other locations · NCT07325552

• ER-100 treatment for open-angle glaucoma and non-arteritic anterior ischemic optic neuropathy

  This trial will test a single dose of ER-100 gene therapy in adults with open-angle glaucoma or NAION to see if it is safe and what side effects occur.

  Recruiting at 4 sites Phase 1 Life Biosciences Inc. · Glendale, California and 3 other locations · NCT07290244

• VisiPlate aqueous shunt to lower eye pressure in refractory open-angle glaucoma

  This trial will test whether the VisiPlate implant can safely lower intraocular pressure in people whose open-angle glaucoma hasn't been controlled by medicines or prior surgeries.

  Recruiting at 12 sites Avisi Technologies Inc. · Glendale, Arizona and 13 other locations · NCT07220876

• Evaluating DSLT for Newly Diagnosed Open Angle Glaucoma Patients

  This study is testing if a new procedure called DSLT can help people with newly diagnosed open angle glaucoma lower their eye pressure without needing medication for a year.

  Recruiting Barnet Dulaney Perkins Eye Centers · Mesa, Arizona · NCT06933836

• Comparing treatments for open-angle glaucoma and cataract

  This study is testing a new eye surgery for people with both open-angle glaucoma and cataracts to see if it can lower eye pressure and improve their vision and quality of life.

  Recruiting Faculdade de Ciências Médicas de Minas Gerais · Belo Horizonte, Minas Gerais · NCT06865235

• Evaluating the long-term safety and effectiveness of a modified silicone tube for glaucoma treatment

  This study is testing a new silicone tube to see if it safely helps people with glaucoma manage their eye pressure and maintain good vision over the long term.

  Recruiting Davinci LTD · Tbilisi · NCT06691555

Related topics

Quick answers

How many Open Angle Glaucoma (OAG) clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (8 trials), South Africa (1 trial), Poland (1 trial), Georgia (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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