Clinical trial Recruiting at 1 site Observational Ages 30 and up

Evaluating DSLT for Newly Diagnosed Open Angle Glaucoma Patients

Official title: How Does First Line Treatment With DSLT Perform in Treatment-naïve Patients With Newly Diagnosed Primary Open Angle Glaucoma

Run by Barnet Dulaney Perkins Eye Centers · NCT06933836 · Data updated 2026-11-12

This study is testing if a new procedure called DSLT can help people with newly diagnosed open angle glaucoma lower their eye pressure without needing medication for a year.

Quick facts

Study typeObservational
Ages30 Years and up
SexAll
Enrollment55 (estimated)
SponsorBarnet Dulaney Perkins Eye Centers
Research network
Locations1 site (Mesa, Arizona)
StatusRecruiting
StartedMarch 31, 2025
Main results expectedNovember 30, 2027
Study endsDecember 31, 2027
Registry record updatedApril 18, 2025
Trial IDNCT06933836 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 30 and older with newly diagnosed primary open angle glaucoma and an IOP between 18-26 mmHg.

Probably not a fit

Patients with a history of prior glaucoma treatment or those with uncontrolled systemic diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effectiveness of the DSLT procedure in treatment-naïve patients diagnosed with primary open angle glaucoma. The goal is to achieve a significant reduction in intraocular pressure (IOP) without the need for medication over a 12-month period. Eligible participants include those aged 30 and older with mild to moderate glaucoma, who have not received any prior treatment. The study aims to provide insights into how DSLT can help manage glaucoma effectively.

Why it matters

Potential benefit: If successful, this approach could allow patients to manage their glaucoma effectively without the need for ongoing medication.

How similar studies have gone: Other studies have shown promising results with similar laser treatments for glaucoma, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Primary open angle glaucoma
* Patients age 30 or greater with an IOP of 18-26 mmHg
* Mild to moderate POAG patients (mild or moderate according to the AAO PPP Guidelines)
* DSLT procedure

Exclusion Criteria:

* History of prior glaucoma treatment - this includes past medication use (in either eye), previous lasers or incisional surgery
* Angle closure patients
* Ocular Hypertension
* Baseline VF MD of worse than -12dB
* Uncontrolled systemic microvascular disease (eg. HTN, DM)
* Subjects with peri-limbal findings (e.g. melanosis, tumors, extensive pterygium, significant senile arcus and pterygium)

Where it's running

  • Barnet Dulaney Perkins Eye Centers
    Mesa, Arizona, United States
    Recruiting

Study contacts

  • Principal investigator: Christine Funke, Medical Doctor — Barnet Dulaney Perkins Eye Centers
  • Study coordinator: Derek J Arnson, Master of Education
  • Email: derek.arnson@researchavp.com
  • Phone: 4804201005

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.