Evaluating DSLT for Newly Diagnosed Open Angle Glaucoma Patients
Official title: How Does First Line Treatment With DSLT Perform in Treatment-naïve Patients With Newly Diagnosed Primary Open Angle Glaucoma
Run by Barnet Dulaney Perkins Eye Centers · NCT06933836 · Data updated 2026-11-12
This study is testing if a new procedure called DSLT can help people with newly diagnosed open angle glaucoma lower their eye pressure without needing medication for a year.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 30 Years and up |
| Sex | All |
| Enrollment | 55 (estimated) |
| Sponsor | Barnet Dulaney Perkins Eye Centers Research network |
| Locations | 1 site (Mesa, Arizona) |
| Status | Recruiting |
| Started | March 31, 2025 |
| Main results expected | November 30, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | April 18, 2025 |
| Trial ID | NCT06933836 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 30 and older with newly diagnosed primary open angle glaucoma and an IOP between 18-26 mmHg.
✕Probably not a fit
Patients with a history of prior glaucoma treatment or those with uncontrolled systemic diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the effectiveness of the DSLT procedure in treatment-naïve patients diagnosed with primary open angle glaucoma. The goal is to achieve a significant reduction in intraocular pressure (IOP) without the need for medication over a 12-month period. Eligible participants include those aged 30 and older with mild to moderate glaucoma, who have not received any prior treatment. The study aims to provide insights into how DSLT can help manage glaucoma effectively.
Why it matters
Potential benefit: If successful, this approach could allow patients to manage their glaucoma effectively without the need for ongoing medication.
How similar studies have gone: Other studies have shown promising results with similar laser treatments for glaucoma, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Primary open angle glaucoma * Patients age 30 or greater with an IOP of 18-26 mmHg * Mild to moderate POAG patients (mild or moderate according to the AAO PPP Guidelines) * DSLT procedure Exclusion Criteria: * History of prior glaucoma treatment - this includes past medication use (in either eye), previous lasers or incisional surgery * Angle closure patients * Ocular Hypertension * Baseline VF MD of worse than -12dB * Uncontrolled systemic microvascular disease (eg. HTN, DM) * Subjects with peri-limbal findings (e.g. melanosis, tumors, extensive pterygium, significant senile arcus and pterygium)
Where it's running
-
Barnet Dulaney Perkins Eye Centers
Mesa, Arizona, United States Recruiting
Study contacts
- Principal investigator: Christine Funke, Medical Doctor — Barnet Dulaney Perkins Eye Centers
- Study coordinator: Derek J Arnson, Master of Education
- Email: derek.arnson@researchavp.com
- Phone: 4804201005
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Eye drops Rhopressa vs Timolol to protect nerve cells in glaucoma
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This study tests a travoprost implant (iDose TR) given inside the eye to people with open-angle glaucoma or high eye pressure in an office setting to see if it is safe.
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Direct (non-contact) laser versus standard selective laser for treating glaucoma
This test compares a newer non-contact laser (DSLT) with the standard SLT to see if it lowers eye pressure just as well in adults with open-angle glaucoma or ocular hypertension.
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This study will see if the new G2-TRIO inserter reliably and safely delivers the 75 mcg Travoprost intracameral implant in adults with open-angle glaucoma or ocular hypertension.
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This trial tests whether adding either two iStent inject implants or a Kahook Dual Blade goniotomy at the time of cataract surgery helps people with open-angle glaucoma lower eye pressure or reduce glaucoma medications.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.