Evaluating DSLT for Newly Diagnosed Open Angle Glaucoma Patients

How Does First Line Treatment With DSLT Perform in Treatment-naïve Patients With Newly Diagnosed Primary Open Angle Glaucoma

Barnet Dulaney Perkins Eye Centers · NCT06933836

This study is testing if a new procedure called DSLT can help people with newly diagnosed open angle glaucoma lower their eye pressure without needing medication for a year.

Quick facts

Study typeObservational
Enrollment55 (estimated)
Ages30 Years and up
SexAll
SponsorBarnet Dulaney Perkins Eye Centers (network)
Locations1 site (Mesa, Arizona)
Trial IDNCT06933836 on ClinicalTrials.gov

What this trial studies

This observational study investigates the effectiveness of the DSLT procedure in treatment-naïve patients diagnosed with primary open angle glaucoma. The goal is to achieve a significant reduction in intraocular pressure (IOP) without the need for medication over a 12-month period. Eligible participants include those aged 30 and older with mild to moderate glaucoma, who have not received any prior treatment. The study aims to provide insights into how DSLT can help manage glaucoma effectively.

Who should consider this trial

Good fit: Ideal candidates are adults aged 30 and older with newly diagnosed primary open angle glaucoma and an IOP between 18-26 mmHg.

Not a fit: Patients with a history of prior glaucoma treatment or those with uncontrolled systemic diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could allow patients to manage their glaucoma effectively without the need for ongoing medication.

How similar studies have performed: Other studies have shown promising results with similar laser treatments for glaucoma, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Primary open angle glaucoma
* Patients age 30 or greater with an IOP of 18-26 mmHg
* Mild to moderate POAG patients (mild or moderate according to the AAO PPP Guidelines)
* DSLT procedure

Exclusion Criteria:

* History of prior glaucoma treatment - this includes past medication use (in either eye), previous lasers or incisional surgery
* Angle closure patients
* Ocular Hypertension
* Baseline VF MD of worse than -12dB
* Uncontrolled systemic microvascular disease (eg. HTN, DM)
* Subjects with peri-limbal findings (e.g. melanosis, tumors, extensive pterygium, significant senile arcus and pterygium)

Where this trial is running

Mesa, Arizona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Open Angle Glaucoma, Glaucoma, DSLT, Interocular Pressure

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.