Condition

Oligodendroglioma clinical trials and research

• 14Clinical trials
• 10Countries

Newest Oligodendroglioma clinical trials

All recruiting trials (14)

• Safusidenib in IDH1-mutant glioma after vorasidenib progression

  This trial tests safusidenib in people with IDH1-mutant glioma who progressed on vorasidenib and did not need immediate chemo or radiation.

  Recruiting at 2 sites Phase 2 Nuvation Bio Inc. · Los Angeles, California and 11 other locations · NCT07703436

• Pre-radiation chemotherapy for high-grade glioma

  Researchers are testing whether giving temozolomide before radiation can help patients with newly diagnosed high-grade gliomas see better outcomes and clearer MRI results after treatment.

  Recruiting Phase 2 Cooper Norcross Health · Camden, New Jersey · NCT07439172

• FearLess for adults with malignant brain tumors and their caregivers

  This project will test whether the FearLess psychological program can reduce fear of cancer recurrence in adults with primary malignant brain tumors and their nonprofessional caregivers.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06989086

• Home-based self-management and cognitive training for brain tumor survivors

  This trial will try a home-based cognitive coaching program to see if it improves thinking and quality of life for adults who survived non-glioblastoma brain tumors, with optional caregiver participation.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06930846

• Treatment of high-grade glioma in young patients using olutasidenib and temozolomide

  This study is testing if a new combination of olutasidenib and temozolomide can help young patients with high-grade gliomas that have a specific mutation feel better after their radiotherapy.

  Recruiting at 8 sites Phase 2 Rigel Pharmaceuticals · Aurora, Colorado and 19 other locations · NCT06161974

• Treatment for young patients with relapsed or refractory brain tumors

  This study is testing a new way to deliver cancer drugs directly to the brain tumors of young patients under 22 who have not responded to other treatments, to see if it helps them feel better.

  Recruiting Phase 1/2 University of Miami · Miami, Florida · NCT05956821

• Combining sintilimab and low-dose bevacizumab for treating relapsed oligodendroglioma

  This study is testing if a new combination of two drugs can help adults with relapsed oligodendroglioma live longer and feel better compared to standard treatment.

  Recruiting Phase 2 Henan Provincial People's Hospital · Zhengzhou, Henan · NCT05512351

• Combining All-Trans Retinoic Acid and PD-1 Inhibition for Recurrent IDH-Mutant Glioma

  This study is testing if a combination of a vitamin A derivative and a cancer immunotherapy can help people with recurrent IDH-mutant glioma feel better and fight their tumors.

  Recruiting Phase 2 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT05345002

• Improving brain function and quality of life for patients with newly diagnosed gliomas.

  This study is testing a new combination of chemotherapy and radiotherapy to see if it can improve brain function and quality of life for people with newly diagnosed oligodendrogliomas.

  Recruiting at 19 sites Phase 3 University Hospital Heidelberg · Heidelberg, Baden-Wurttemberg and 18 other locations · NCT05331521

• Safusidenib as maintenance therapy for IDH1‑mutant astrocytoma and oligodendroglioma

  This trial tests whether the oral drug safusidenib can help people with IDH1‑mutant astrocytomas or oligodendrogliomas remain progression‑free longer after surgery and standard radiation/chemotherapy.

  Recruiting at 59 sites Phase 3 Nuvation Bio Inc. · Birmingham, Alabama and 60 other locations · NCT05303519

• Comparing proton and photon therapy for IDH-mutated gliomas

  This study tests whether proton therapy can be as effective as traditional photon therapy for people with certain types of brain tumors while possibly improving their quality of life.

  Recruiting Oslo University Hospital · Oslo · NCT05190172

• Delayed radiotherapy for low-grade oligodendrogliomas

  This study is testing whether waiting to give radiotherapy to patients with low-grade oligodendrogliomas until their tumors grow can help protect their brain function while still keeping them alive longer.

  Recruiting at 13 sites Phase 3 Hospices Civils de Lyon · Amiens and 25 other locations · NCT04702581

• Proton therapy for brain tumors

  This study is testing whether proton therapy can be a better treatment option for patients with certain brain tumors by comparing it to traditional radiation methods to see if it can reduce harm to healthy tissues.

  Recruiting at 3 sites Maastricht Radiation Oncology · Maastricht, Limburg and 2 other locations · NCT04648462

• Chemotherapy and radiation therapy for treating certain types of gliomas

  This study is testing if a combination of a chemotherapy drug and radiation therapy can help people with certain types of brain tumors live longer and feel better.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04623931

Related topics

Quick answers

How many Oligodendroglioma clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (9 trials), China (2 trials), Germany (2 trials), Australia (2 trials), Netherlands (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 3: 3, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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