Condition

Monoclonal Gammopathy of Undetermined Significance clinical trials and research

• 12Clinical trials
• 4Countries

Newest Monoclonal Gammopathy of Undetermined Significance clinical trials

All recruiting trials (12)

• Prolonged overnight fasting combined with a Mediterranean-style diet for people with multiple myeloma or precursor conditions

  This program will test whether longer overnight fasting paired with a Mediterranean-style eating plan is doable for adults with MGUS, smoldering myeloma, or newly diagnosed multiple myeloma who are starting treatment.

  Recruiting University of Miami · Miami, Florida · NCT07446777

• Using Whole Body MRI to Improve Cancer Detection

  This study is testing if Whole Body MRI can help find bone and soft tissue problems in people with different types of cancer, like lymphoma and advanced prostate and breast cancer.

  Recruiting at 2 sites Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS · Bologna, BO and 2 other locations · NCT06895291

• Frequency of GBA and PSAP Gene Variants in Patients with MM or MGUS

  This study tests whether people with multiple myeloma or MGUS have certain variants in the GBA and PSAP genes.

  Recruiting University Hospital, Rouen · Rouen and 1 other locations · NCT06559033

• Network for early diagnosis and management of AL amyloidosis in Italy

  This study is trying to set up a network in Italy to help doctors find AL amyloidosis earlier in patients who are at risk, so they can get treatment sooner and improve their health.

  Recruiting at 4 sites Fondazione IRCCS Policlinico San Matteo di Pavia · Bari and 3 other locations · NCT06383143

• Exploring the effects of a plant-based diet and supplements on smoldering multiple myeloma

  This study is testing whether a plant-based diet and certain supplements can change butyrate levels in the stool of people with smoldering multiple myeloma.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT06055894

• Screening for M-protein in relatives of multiple myeloma patients in China

  This study is trying to see if screening for a specific protein in the blood can help find early signs of a blood condition in family members of people with multiple myeloma in China.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT05965115

• Comparing a plant-based diet with supplements and placebo for people with MGUS or smoldering multiple myeloma

  This study is testing whether a plant-based diet combined with certain supplements can change butyrate levels in people with MGUS or smoldering multiple myeloma.

  Recruiting at 8 sites Memorial Sloan Kettering Cancer Center · Atlanta, Georgia and 7 other locations · NCT05640843

• Understanding different types of multiple myeloma precursor conditions

  This study is trying to tell the difference between two early stages of multiple myeloma, smoldering multiple myeloma and monoclonal gammopathy of undetermined significance, to better understand how they progress or stay stable.

  Recruiting University of Miami · Miami, Florida · NCT05361694

• Assessing quality of life in patients with asymptomatic monoclonal gammopathies

  This study looks at how living with monoclonal gammopathy of undetermined significance and smoldering multiple myeloma affects people's quality of life and anxiety over three years.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT05136807

• Investigating sleep apnea in patients with certain blood disorders

  This study is trying to see if sleep apnea affects the progression of blood disorders like MGUS and multiple myeloma in patients.

  Recruiting University of Iowa · Iowa City, Iowa · NCT04114084

• Observational study on monoclonal gammopathies leading to myeloma

  This study is trying to find out if certain markers in blood samples can help predict when people with MGUS or smoldering myeloma might develop full-blown multiple myeloma.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT02726750

• Registry and sample resource for patients with plasma cell disorders

  This study is gathering information from patients with plasma cell disorders like multiple myeloma to see how to improve their treatment and quality of life.

  Recruiting Ohio State University Comprehensive Cancer Center · Columbus, Ohio · NCT01408225

Related topics

Quick answers

How many Monoclonal Gammopathy of Undetermined Significance clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (8 trials), Italy (2 trials), China (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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