Condition
Smoldering Plasma Cell Myeloma clinical trials and research
Research outlook What's coming for Multiple myeloma: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 5 Smoldering Plasma Cell Myeloma clinical trials that are recruiting, at sites in 2 countries (most in United States (5), Puerto Rico (1)). By phase: Phase 3 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 2Countries
Newest Smoldering Plasma Cell Myeloma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Improving quality of life and immune function in multiple myeloma patients through lifestyle changes | — | Buffalo, New York | Recruiting | Apr 5, 2022 |
| Assessing quality of life in patients with asymptomatic monoclonal gammopathies | — | Houston, Texas | Recruiting | Nov 29, 2021 |
| Treatment of smoldering multiple myeloma with iberdomide and dexamethasone | Phase 2 | Atlanta, Georgia | Recruiting | Mar 1, 2021 |
| Combining lenalidomide and dexamethasone with or without daratumumab for high-risk smoldering myeloma | Phase 3 | Birmingham, Alabama and 747 other locations | Recruiting | May 6, 2019 |
| Observational study on monoclonal gammopathies leading to myeloma | — | Houston, Texas | Recruiting | Apr 4, 2016 |
All recruiting trials (5)
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Improving quality of life and immune function in multiple myeloma patients through lifestyle changes
This study is testing whether lifestyle changes like exercise and diet can improve the immune system and quality of life for people with multiple myeloma.
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Assessing quality of life in patients with asymptomatic monoclonal gammopathies
This study looks at how living with monoclonal gammopathy of undetermined significance and smoldering multiple myeloma affects people's quality of life and anxiety over three years.
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Treatment of smoldering multiple myeloma with iberdomide and dexamethasone
This study is testing if a new treatment combining iberdomide and dexamethasone can help people with smoldering multiple myeloma live longer and feel better.
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Combining lenalidomide and dexamethasone with or without daratumumab for high-risk smoldering myeloma
This study is testing if adding daratumumab to the standard treatment of lenalidomide and dexamethasone can help people with high-risk smoldering multiple myeloma live longer and feel better.
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Observational study on monoclonal gammopathies leading to myeloma
This study is trying to find out if certain markers in blood samples can help predict when people with MGUS or smoldering myeloma might develop full-blown multiple myeloma.
Related topics
Quick answers
How many Smoldering Plasma Cell Myeloma clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (5 trials), Puerto Rico (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.