Registry and sample resource for patients with plasma cell disorders
Official title: Buckeye Surveillance, Contact, and Research for Multiple Myeloma and Amyloidosis
Run by Ohio State University Comprehensive Cancer Center · NCT01408225 · Data updated 2026-11-12
This study is gathering information from patients with plasma cell disorders like multiple myeloma to see how to improve their treatment and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Ohio State University Comprehensive Cancer Center Academic / other |
| Locations | 1 site (Columbus, Ohio) |
| Status | Recruiting |
| Started | March 17, 2011 |
| Main results expected | March 2050 |
| Study ends | March 2050 |
| Registry record updated | March 23, 2026 |
| Trial ID | NCT01408225 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with plasma cell dyscrasias, such as multiple myeloma or AL amyloidosis.
✕Probably not a fit
Patients who are incarcerated will not benefit from this study due to their lack of access to the necessary clinical resources.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather comprehensive data on patients diagnosed with plasma cell dyscrasias, including multiple myeloma and AL amyloidosis, to enhance their quality of life and longevity. The research involves creating a database that tracks treatment effectiveness, patient experiences, and survival outcomes. Additionally, the study provides patients with access to clinical consultations and information about local support resources. By engaging with patients across Ohio, the investigators hope to develop targeted interventions to reduce morbidity and mortality associated with these conditions.
Why it matters
Potential benefit: If successful, this initiative could lead to improved treatment strategies and support for patients with plasma cell disorders.
How similar studies have gone: Other studies focusing on patient registries and tissue banking for rare diseases have shown promise in improving patient outcomes and advancing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion: Diagnosis of a plasma cell dyscrasia Exclusion: Prisoners are excluded from participation as they have no standard access to the Ohio State myeloma clinic and would impede the research objective of this protocol.
Where it's running
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Ohio State University Medical Center
Columbus, Ohio, United States Recruiting
Study contacts
- Principal investigator: Don Benson, MD — Ohio State University
- Study coordinator: The Ohio State University Comprehensive Cancer Center
- Email: OSUCCCClinicaltrials@osumc.edu
- Phone: 1-800-293-5066
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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SMS text check-ins to track symptoms for people with plasma cell disorders
This study tests whether daily SMS symptom prompts are feasible and acceptable for adults starting treatment for multiple myeloma or AL amyloidosis.
-
Tec Dara for newly diagnosed multiple myeloma with light chain amyloidosis
This study tests whether tec listamab plus daratumumab can help newly diagnosed multiple myeloma with AL amyloidosis and whether the combination is safe.
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How the IGLV1-44 light chain causes AL amyloidosis and POEMS
This project tests whether specific IGLV1-44 light‑chain sequences drive AL amyloidosis and POEMS and whether nanobodies can recognize and stabilize those light chains in adults with AL amyloidosis, POEMS, or multiple myeloma.
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How N-glycosylation of light chains affects AL amyloidosis diagnosis and treatment
This project will test whether a sugar modification called N-glycosylation on immunoglobulin light chains helps cause disease or changes how AL amyloidosis and related monoclonal gammopathies behave in adults.
-
Prolonged overnight fasting combined with a Mediterranean-style diet for people with multiple myeloma or precursor conditions
This program will test whether longer overnight fasting paired with a Mediterranean-style eating plan is doable for adults with MGUS, smoldering myeloma, or newly diagnosed multiple myeloma who are starting treatment.
-
Using Whole Body MRI to Improve Cancer Detection
This study is testing if Whole Body MRI can help find bone and soft tissue problems in people with different types of cancer, like lymphoma and advanced prostate and breast cancer.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.