Condition

MGMT-Methylated Glioblastoma clinical trials and research

• 4Clinical trials
• 5Countries

Newest MGMT-Methylated Glioblastoma clinical trials

All recruiting trials (4)

• Adding ruxolitinib to standard radiation and temozolomide for newly diagnosed glioblastoma

  This trial will try whether adding the oral drug ruxolitinib to standard radiation and temozolomide helps adults newly diagnosed with glioblastoma.

  Recruiting at 2 sites Phase 2 Baptist Health South Florida · Miami, Florida and 1 other locations · NCT06991101

• G-CSF after chemo-radiation for MGMT-methylated glioblastoma

  This test checks whether giving G-CSF after standard chemo-radiation helps protect brain structure and thinking in adults with newly diagnosed MGMT-methylated glioblastoma.

  Recruiting Phase 2 Massachusetts General Hospital · Boston, Massachusetts · NCT06649851

• Combination of DB107-RRV, DB107-FC, and radiation therapy for high grade glioma

  This study is testing a new combination of treatments for people with newly diagnosed high grade glioma to see if it helps them live longer without their cancer getting worse after surgery.

  Recruiting at 5 sites Phase 1/2 University of California, San Francisco · Los Angeles, California and 4 other locations · NCT06504381

• Adding lomustine to standard care for MGMT‑methylated glioblastoma

  This trial tests whether giving lomustine together with temozolomide and radiation helps adults with newly diagnosed, MGMT‑methylated, IDH‑wildtype glioblastoma live longer.

  Recruiting at 12 sites Phase 3 Vastra Gotaland Region · Graz and 19 other locations · NCT06419946

Related topics

Quick answers

How many MGMT-Methylated Glioblastoma clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (3 trials), Austria (1 trial), Denmark (1 trial), Norway (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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