Condition
ME/CFS clinical trials and research
As of November 12, 2026, Find a Trial lists 8 ME/CFS clinical trials that are recruiting, at sites in 4 countries (most in United States (4), Germany (2), Israel (1)). 1 was first registered in the last 30 days. By phase: Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 8Clinical trials
- 1New in 30 days
- 4Countries
Newest ME/CFS clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Whole-body Cryotherapy for Fatigue in ME/CFS, Fibromyalgia, Long COVID | — | Oxford, Oxon | Recruiting | Oct 14, 2026 |
| Hyperbaric Oxygen Therapy for ME/CFS | — | Zrifin | Recruiting | Jun 2, 2026 |
| Cognitive rehabilitation for ME/CFS brain fog | — | Birmingham, Alabama | Recruiting | Apr 13, 2026 |
| Outreach medical care for housebound adults with Post-COVID syndrome or ME/CFS | — | Hanover | Recruiting | Jan 20, 2026 |
| Improving life for patients with chronic fatigue syndrome | Phase 2 | Boston, Massachusetts | Recruiting | Apr 16, 2024 |
| Using probiotics to treat Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | Phase 2 | Fort Lauderdale, Florida | Recruiting | Jan 18, 2024 |
| Registry for ME/CFS patients in Germany | — | Munich, Bavaria | Recruiting | Mar 21, 2023 |
| A platform for collecting health data on ME/CFS and Long Covid | — | Delafield, Wisconsin | Recruiting | Mar 19, 2021 |
All recruiting trials (8)
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Whole-body Cryotherapy for Fatigue in ME/CFS, Fibromyalgia, Long COVID
This study tests whether brief, repeated exposure to extreme cold can help reduce fatigue and related symptoms in adults with ME/CFS, fibromyalgia, or Long COVID compared to healthy controls.
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Hyperbaric Oxygen Therapy for ME/CFS
This study tests whether hyperbaric oxygen therapy can help people with mild to moderate ME/CFS.
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Cognitive rehabilitation for ME/CFS brain fog
Researchers are testing two cognitive rehabilitation approaches to see which helps adults with ME/CFS and brain fog better manage thinking and daily tasks.
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Outreach medical care for housebound adults with Post-COVID syndrome or ME/CFS
This project will try home visits and remote assessments to learn the symptoms and care needs of adults who are housebound with Post‑COVID syndrome or ME/CFS.
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Improving life for patients with chronic fatigue syndrome
This study is testing if two medications can help people aged 18-65 with chronic fatigue syndrome feel better and manage their symptoms.
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Using probiotics to treat Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This study is testing if a new probiotic can help people aged 45 to 70 with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and possibly irritable bowel syndrome feel better.
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Registry for ME/CFS patients in Germany
This study is creating a large registry to collect health information from people of all ages with ME/CFS in Germany, especially those affected by long-term COVID-19 effects, to help improve understanding and treatment of the condition.
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A platform for collecting health data on ME/CFS and Long Covid
This study is trying to collect health information from adults with ME/CFS and Long Covid to help researchers better understand these conditions and improve future treatments.
Related topics
Quick answers
How many ME/CFS clinical trials are recruiting right now?
8, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in United States (4 trials), Germany (2 trials), Israel (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.