Condition
Chronic Fatigue Syndrome (CFS) clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Chronic Fatigue Syndrome (CFS) clinical trials that are recruiting, at sites in 4 countries (most in United States (2), Poland (1), Pakistan (1)). By phase: Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 4Countries
Newest Chronic Fatigue Syndrome (CFS) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Hydrogen water for ME/CFS: a 16-week comparison to placebo | — | Stony Brook, New York | Recruiting | Aug 7, 2026 |
| Photobiomodulation for Chronic Fatigue Syndrome: can light therapy help fatigue and quality of life? | — | Larkana, Sindh | Recruiting | Apr 22, 2026 |
| Cognitive rehabilitation for ME/CFS brain fog | — | Birmingham, Alabama | Recruiting | Apr 13, 2026 |
| Physical exercise and neuromodulation for fibromyalgia-related pain, sleep, and fatigue | — | Warsaw, Masovian Voivodeship | Recruiting | Nov 21, 2025 |
| Lingzhi (CP003) for chronic fatigue syndrome and post-COVID fatigue | Phase 2/3 | Hong Kong | Recruiting | Dec 18, 2024 |
All recruiting trials (5)
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Hydrogen water for ME/CFS: a 16-week comparison to placebo
This 16-week pilot study tests whether hydrogen water helps reduce fatigue and improve physical function in adults with ME/CFS, compared with a placebo.
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Photobiomodulation for Chronic Fatigue Syndrome: can light therapy help fatigue and quality of life?
This study tests whether low-level laser therapy can reduce fatigue and improve quality of life in adults with chronic fatigue syndrome, compared with a sham treatment.
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Cognitive rehabilitation for ME/CFS brain fog
Researchers are testing two cognitive rehabilitation approaches to see which helps adults with ME/CFS and brain fog better manage thinking and daily tasks.
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Physical exercise and neuromodulation for fibromyalgia-related pain, sleep, and fatigue
This project will try structured treadmill/balance training or gentle transcutaneous neuromodulation, each combined with usual physiotherapy, to see if they reduce pain, improve sleep, and lower fatigue in adults with fibromyalgia and chronic fatigue.
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Lingzhi (CP003) for chronic fatigue syndrome and post-COVID fatigue
This trial tests whether the Lingzhi supplement CP003 can help people with chronic fatigue syndrome or fatigue after COVID-19 and whether it is safe to take.
Related topics
Quick answers
How many Chronic Fatigue Syndrome (CFS) clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in United States (2 trials), Poland (1 trial), Pakistan (1 trial), Hong Kong (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.