Condition

Lung Cancers clinical trials and research

• 17Clinical trials
• 15NIH research projects
• 10Countries

Newest Lung Cancers clinical trials

All recruiting trials (17)

• Shape-sensing robotic bronchoscopy to diagnose peripheral lung nodules

  This tests a shape-sensing robotic bronchoscopy to see if it can get tissue samples from adults in Korea with peripheral lung nodules.

  Recruiting Ulsan University Hospital · Ulsan · NCT07057648

• AVZO-1418 alone and with other treatments for advanced epithelial solid tumors

  This trial will test whether intravenous AVZO-1418, alone or with other cancer drugs, is safe and helps adults with locally advanced or metastatic epithelial solid tumors, including some lung cancers.

  Recruiting at 27 sites Phase 1/2 Avenzo Therapeutics, Inc. · Gilbert, Arizona and 26 other locations · NCT07038343

• Online and in-person exercise programs for cancer survivors in Canada

  This study is testing whether online and in-person exercise programs can help cancer survivors in Canada stay active and improve their health.

  Recruiting at 5 sites University of Calgary · Calgary, Alberta and 4 other locations · NCT06960291

• General anesthesia versus conscious sedation for radial endobronchial ultrasound

  This trial will see if general anesthesia or conscious sedation gives better diagnostic results for adults undergoing radial endobronchial ultrasound to sample peripheral lung nodules.

  Recruiting at 2 sites Institut universitaire de cardiologie et de pneumologie de Québec, University Laval · Québec, Quebec and 3 other locations · NCT06950515

• Super1 TCR-T for NY-ESO-1–positive advanced solid tumors

  This trial tests whether a single infusion of Super1 TCR-T can help people with advanced sarcoma, lung cancer, or melanoma whose tumors are HLA-A*02 positive and express NY-ESO-1.

  Recruiting Phase 1 Guangzhou FineImmune Biotechnology Co., LTD. · Guangzhou, Gaungdong · NCT06942143

• Using a new molecular probe for early diagnosis of tumors

  This study is testing a new imaging tool to see if it can help doctors find different types of tumors earlier in patients aged 18 to 75 who already have confirmed tumor lesions.

  Recruiting Nanjing First Hospital, Nanjing Medical University · Nanjing, Jiangsu · NCT06937112

• Acupuncture with PD‑1/PD‑L1 immunotherapy for advanced lung cancer

  This trial will test whether adding acupuncture to PD‑1/PD‑L1 immunotherapy plus chemotherapy helps people with advanced lung cancer have better tumor responses and fewer side effects.

  Recruiting at 3 sites Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Hefei, Anhui and 2 other locations · NCT06926140

• Early‑phase KESONOTIDE™ treatment for solid tumors

  This trial tests an oral drug called KESONOTIDE™ (a vimentin inhibitor) to see if it is safe and tolerable in adults with advanced or metastatic solid tumors like prostate, breast, lung, ovarian cancer, or glioblastoma.

  Recruiting at 3 sites Phase 1/2 Filamon LTD · Kogarah, New South Wales and 2 other locations · NCT06926075

• Blood test to detect early lung cancer in high-risk heavy smokers

  This project will test whether a blood-based test can detect early, symptom-free lung cancer in current or former heavy smokers.

  Recruiting Everest Detection, Inc. · Oklahoma City, Oklahoma · NCT06816121

• Comparing two pain management techniques for thoracic surgery

  This study tests which pain management method works better for people having lung cancer surgery: an erector spinae block with liposomal bupivacaine or intercostal nerve blocks.

  Recruiting Phase 3 George Washington University · Washington D.C., District of Columbia · NCT06810375

• Higher-dose, short-course chest radiation that spares the esophagus

  This trial will try a five-session, higher-dose, esophagus-sparing radiation schedule for adults with intrathoracic tumors who need palliative chest radiation, compared with standard palliative radiation.

  Recruiting at 4 sites London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Kelowna, British Columbia and 3 other locations · NCT06794125

• Targeted high- and low-dose radiation with chemotherapy and immunotherapy for advanced lung cancer

  This trial tests whether adding focused high‑dose and low‑dose radiation to chemotherapy and immunotherapy helps people with advanced lung cancer whose disease progressed after prior immunotherapy.

  Recruiting Phase 2 Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT06775678

• Modified Bufei Decoction to relieve post-surgery symptoms and support recovery for older lung cancer patients

  This trial tests whether taking modified Bufei Tang granules twice daily for 28 days can reduce post-surgery cough, breathlessness, and fatigue in people aged 65 and older who had lung cancer surgery.

  Recruiting at 2 sites Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality and 1 other locations · NCT06674252

• AI-assisted non-contrast CT for detecting multiple cancers

  This study is testing whether an AI tool can help find different types of cancer earlier in healthy people getting routine check-ups.

  Recruiting Changhai Hospital · Shanghai, Shanghai Municipality · NCT06632886

• Innovative care program for lung cancer survivors

  This study is testing a new care program designed to help lung cancer survivors in Kentucky feel better and improve their quality of life compared to standard care.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT05857995

• Analysis of blood tumor markers for cancer diagnosis and treatment monitoring

  This study is testing whether a simple blood test can replace traditional tissue biopsies to help diagnose cancer and monitor how well treatments are working.

  Recruiting at 2 sites Institut du Cancer de Montpellier - Val d'Aurelle · Montpellier and 1 other locations · NCT04025541

• Research on health inequality and genetic disparity in cardiovascular diseases

  This study is trying to understand how health differences and genetics affect heart diseases in people from various ethnic backgrounds in the UK to help improve treatments for everyone.

  Recruiting Future Genetics Limited · Wolverhampton, West Midlands · NCT03987633

NIH-funded research (15)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• TRIM28 Inhibition for NOTCH2-Mutant Small Cell Lung Cancer

  A new approach aims to exploit a weakness in a subset of small cell lung cancer by turning on immune-related signals when NOTCH2 is lost, potentially making tumors more visible to the immune system.

  NIH research Dana-Farber Cancer Inst · Boston, United States · NIH-11430295

• Genomic factors shaping lung cancer risk in Native Hawaiians and Pacific Islanders

  This NIH grant focuses on understanding why Native Hawaiians, Pacific Islanders, and African Americans have higher lung cancer risk and poorer outcomes by studying tumor DNA and related molecular patterns.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11375087

• PD-L1 PET tracer to guide immune therapy in non-small cell lung cancer

  A Johns Hopkins team is testing a Gallium-68 PET tracer to better guide immune checkpoint therapy for people with non-small cell lung cancer.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11334314

• Targeting SMARCA2 to treat lung cancers that lack SMARCA4

  This work looks at whether blocking a protein called SMARCA2 can slow or stop lung cancers that have lost the related gene SMARCA4.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11304485

• New medicines for lung cancers caused by KRAS or BRAF changes

  Testing new medicines that block ERK/RAF signaling in people with lung cancer driven by KRAS or BRAF mutations.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11265093

• Understanding lung cancer risks in Native Hawaiians

  This research looks at the genetic differences in lung cancer among Native Hawaiians to better understand why they face higher risks and poorer outcomes.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11141193

• New medicines to fight treatment resistance in breast and lung cancers

  This project aims to create new medications that can help overcome when breast and lung cancers stop responding to current treatments.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-11132688

• Using a special imaging technique to improve cancer immunotherapy for lung cancer patients

  This study is looking to improve treatment for people with non-small cell lung cancer by creating a special imaging tool that helps doctors see how well your immune system is responding to therapy, so they can tailor the treatment just for you.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11113811

• Targeting a specific protein in certain lung cancers

  This study is looking at how a protein called SMARCA2 affects lung cancers that don't have another important protein, SMARCA4, and it aims to find new treatments by figuring out if reducing SMARCA2 can help slow down tumor growth for patients with this specific type of lung cancer.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11108373

• Improving treatments for lung cancer with specific MET mutations

  This study is looking at lung cancer patients with changes in the MET gene to find out how these changes affect treatment, so we can discover better therapy options for everyone dealing with this condition.

  NIH research Fred Hutchinson Cancer Center · Seattle, United States · NIH-11062982

• Investigating the role of human papillomavirus in lung cancers among HIV-positive individuals

  This study is looking into how the human papillomavirus (HPV) might be linked to lung cancer in people living with HIV, using advanced techniques to analyze data from over 1,000 lung cancer samples to help improve our understanding of this connection.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11051154

• Creating new drugs to help treat resistant breast and lung cancers

  This study is looking at new ways to stop certain proteins that help cancer cells resist treatment, especially in HER2-positive breast cancer and KRAS-driven lung cancer, with the hope of creating better therapies that work more effectively for patients like you.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-10900479

• Investigating drug resistance in specific lung cancer mutations and developing targeted treatments

  This study is looking at how certain unusual changes in the EGFR gene make it harder for non-small cell lung cancer patients to respond to current treatments, and it's testing a new drug called poziotinib that might work better for those with these specific changes.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-10818397

• Understanding lung cancer differences among various racial and ethnic groups

  This study looks at how lung cancer affects different racial and ethnic groups to find out why some people are more at risk than others, and it hopes to use this information to help create better prevention and treatment options for everyone.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-10755626

• A tool to predict risks in early stage lung cancers

  This study is testing a new computer tool called CHiRP that helps doctors figure out which patients with early-stage non-small cell lung cancer might not need extra chemotherapy after surgery, so they can avoid unnecessary treatment and side effects.

  NIH research Emory University · Atlanta, United States · NIH-10541900

Related topics

Quick answers

How many Lung Cancers clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in China (7 trials), United States (4 trials), Canada (3 trials), Australia (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 2, Phase 1: 1, Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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