Clinical trial Recruiting at 1 site Interventional Ages 18 and up

AI-assisted non-contrast CT for detecting multiple cancers

Official title: A Prospective Cohort Study Evaluating the Utility of Artificial Intelligence-Assisted Non-Contrast Computed Tomography for Multi-Cancer Screening in Asymptomatic Individuals Undergoing Routine Health Examinations

Run by Changhai Hospital · NCT06632886 · Data updated 2026-11-12

This study is testing whether an AI tool can help find different types of cancer earlier in healthy people getting routine check-ups.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1000000 (estimated)
SponsorChanghai Hospital
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedOctober 7, 2024
Main results expectedOctober 7, 2026
Study endsOctober 7, 2027
Registry record updatedOctober 9, 2024
Trial IDNCT06632886 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are asymptomatic individuals who have undergone non-contrast abdominal or chest CT scans.

Probably not a fit

Patients who have been diagnosed with any of the targeted cancers within the last five years will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of an AI-assisted non-contrast CT imaging model for screening multiple types of cancer, including lung, liver, gastric, colorectal, esophageal, pancreatic, and breast cancers. It aims to enroll 1 million asymptomatic participants who will undergo routine health examinations at designated centers in China. The AI model will automatically detect cancerous lesions, and positive cases will be referred for further imaging and care according to established guidelines. The goal is to improve early detection rates and treatment outcomes for these cancers.

Why it matters

Potential benefit: If successful, this approach could significantly enhance early cancer detection and improve survival rates for patients.

How similar studies have gone: Other studies utilizing AI for cancer detection have shown promising results, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Subject is able and willing to provide informed consent and sign an informed consent form.
2. Subject has undergone an abdominal or chest non-contrast CT scan.

Exclusion Criteria:

1. Subject has been diagnosed with one of the following cancers within the last five years: lung, liver, stomach, colon, esophageal, pancreatic, or breast cancer;
2. Subject has any medical condition that contraindicates high-resolution MRI/CT/Endoscopy;
3. Subject cannot be followed up or is participating in other clinical trials.

Where it's running

  • Changhai Hospital
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.