Comparing two pain management techniques for thoracic surgery
Official title: Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery
Run by George Washington University · NCT06810375 · Data updated 2026-11-12
This study tests which pain management method works better for people having lung cancer surgery: an erector spinae block with liposomal bupivacaine or intercostal nerve blocks.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | George Washington University Academic / other |
| Locations | 1 site (Washington D.C., District of Columbia) |
| Status | Recruiting |
| Started | March 1, 2025 |
| Main results expected | February 28, 2028 |
| Study ends | February 28, 2029 |
| Registry record updated | April 9, 2026 |
| Trial ID | NCT06810375 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients scheduled for video-assisted pulmonary resection, pleurodesis, or decortication.
✕Probably not a fit
Patients with allergies to local anesthetics or those undergoing bilateral surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of two different pain management techniques in patients undergoing thoracic surgery for lung cancers. It compares the erector spinae block with liposomal bupivacaine injections against intercostal nerve blocks. The study aims to determine which method provides better postoperative analgesia. Participants will be monitored for pain levels and recovery outcomes following their surgical procedures.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracic surgery.
How similar studies have gone: Other studies have shown promising results with similar nerve block techniques for pain management, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Video assisted pulmonary resection, pleurodesis or decortication Exclusion Criteria: * Allergy to local anesthetics * Patient undergoing bilateral surgery * Surgery is emergent as deemed by the principal investigator
Where it's running
-
The George Washington University Hospital
Washington D.C., District of Columbia, United States Recruiting
Study contacts
- Study coordinator: Eduard Shaykhinurov, MS
- Email: eshaykhinurov@mfa.gwu.edu
- Phone: 2022038960
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Shape-sensing robotic bronchoscopy to diagnose peripheral lung nodules
This tests a shape-sensing robotic bronchoscopy to see if it can get tissue samples from adults in Korea with peripheral lung nodules.
-
AVZO-1418 alone and with other treatments for advanced epithelial solid tumors
This trial will test whether intravenous AVZO-1418, alone or with other cancer drugs, is safe and helps adults with locally advanced or metastatic epithelial solid tumors, including some lung cancers.
-
Online and in-person exercise programs for cancer survivors in Canada
This study is testing whether online and in-person exercise programs can help cancer survivors in Canada stay active and improve their health.
-
General anesthesia versus conscious sedation for radial endobronchial ultrasound
This trial will see if general anesthesia or conscious sedation gives better diagnostic results for adults undergoing radial endobronchial ultrasound to sample peripheral lung nodules.
-
Super1 TCR-T for NY-ESO-1–positive advanced solid tumors
This trial tests whether a single infusion of Super1 TCR-T can help people with advanced sarcoma, lung cancer, or melanoma whose tumors are HLA-A*02 positive and express NY-ESO-1.
-
Using a new molecular probe for early diagnosis of tumors
This study is testing a new imaging tool to see if it can help doctors find different types of tumors earlier in patients aged 18 to 75 who already have confirmed tumor lesions.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.