Clinical trial Recruiting at 1 site Phase 3 Interventional Ages 18 to 90

Comparing two pain management techniques for thoracic surgery

Official title: Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

Run by George Washington University · NCT06810375 · Data updated 2026-11-12

This study tests which pain management method works better for people having lung cancer surgery: an erector spinae block with liposomal bupivacaine or intercostal nerve blocks.

Quick facts

PhasePhase 3
Study typeInterventional
Ages18 Years to 90 Years
SexAll
Enrollment120 (estimated)
SponsorGeorge Washington University
Academic / other
Locations1 site (Washington D.C., District of Columbia)
StatusRecruiting
StartedMarch 1, 2025
Main results expectedFebruary 28, 2028
Study endsFebruary 28, 2029
Registry record updatedApril 9, 2026
Trial IDNCT06810375 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients scheduled for video-assisted pulmonary resection, pleurodesis, or decortication.

Probably not a fit

Patients with allergies to local anesthetics or those undergoing bilateral surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of two different pain management techniques in patients undergoing thoracic surgery for lung cancers. It compares the erector spinae block with liposomal bupivacaine injections against intercostal nerve blocks. The study aims to determine which method provides better postoperative analgesia. Participants will be monitored for pain levels and recovery outcomes following their surgical procedures.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracic surgery.

How similar studies have gone: Other studies have shown promising results with similar nerve block techniques for pain management, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Video assisted pulmonary resection, pleurodesis or decortication

Exclusion Criteria:

* Allergy to local anesthetics
* Patient undergoing bilateral surgery
* Surgery is emergent as deemed by the principal investigator

Where it's running

  • The George Washington University Hospital
    Washington D.C., District of Columbia, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.