Condition

Knee Pain Chronic clinical trials and research

• 13Clinical trials
• 6Countries

Newest Knee Pain Chronic clinical trials

All recruiting trials (13)

• Brain scans to find links between brain activity and knee replacement outcomes

  This study uses brain MRI before and after knee replacement to see if patterns of brain activity can predict which patients will be satisfied with their surgery.

  Recruiting Ottawa Hospital Research Institute · Ottawa, Ontario · NCT07464080

• 810 nm light therapy for chronic knee pain and synovitis

  This trial will test whether 810 nm light therapy can reduce pain and knee inflammation in adults aged 40–80 with chronic knee pain and ultrasound-confirmed synovitis.

  Recruiting The Hong Kong Polytechnic University · Shenzhen and 1 other locations · NCT07057063

• BioPoly implant for knee cartilage defects

  This study is testing a new knee implant to see if it can help adults with cartilage damage feel better and avoid more surgery compared to standard treatments.

  Recruiting at 4 sites BioPoly LLC · Redwood City, California and 4 other locations · NCT06915363

• Pain Reprocessing Therapy for persistent knee pain after knee replacement

  This trial will test whether Pain Reprocessing Therapy (PRT) delivered by video can reduce persistent knee pain in adults who still have meaningful pain three months after knee replacement.

  Recruiting Phase 2 Weill Medical College of Cornell University · Aurora, Colorado and 1 other locations · NCT06800209

• Evaluating a program for managing chronic knee pain in the elderly

  This study is testing a new program that uses technology to help older adults manage their chronic knee pain better by teaching them self-care strategies.

  Recruiting The University of Hong Kong · Hong Kong · NCT06569836

• Evaluating the effectiveness of embolization for knee pain in total knee prosthesis patients

  This study is testing if a special treatment called embolization can help people with knee pain after knee replacement surgery feel better and move more easily.

  Recruiting at 3 sites Societe Francaise de Rhumatologie · Créteil and 10 other locations · NCT06466330

• Effect of Genicular Nerve Block on Recovery After Knee Surgery

  This study is testing if a special pain-blocking treatment before knee surgery can help patients recover faster and feel better afterward.

  Recruiting Pamukkale University · Denizli, Pamukkale · NCT06239649

• Using vitamin C to reduce pain after knee surgery

  This study is testing if giving vitamin C to people before and after knee surgery can help reduce their pain and improve their quality of life.

  Recruiting at 3 sites Phase 2 University Health Network, Toronto · Toronto, Ontario and 2 other locations · NCT06123715

• Effects of Arm and Leg Exercise on Knee Pain in Osteoarthritis

  This study is testing whether exercising your arms or legs can help reduce knee pain in people with osteoarthritis.

  Recruiting University of Texas, El Paso · El Paso, Texas · NCT06105788

• Improving pain management for knee surgery patients

  This study is testing if a new way of managing pain that combines savoring meditation with education about pain can help people with knee osteoarthritis feel better after knee surgery.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT06038240

• Focused shockwave therapy for knee arthritis

  This study is testing if focused shockwave therapy can help relieve knee pain and improve movement in people with knee arthritis who haven't found relief from other treatments.

  Recruiting at 2 sites Kessler Foundation · Cedar Knolls, New Jersey and 1 other locations · NCT05596591

• Mindfulness interventions for military patients after knee surgery

  This study tests if mindfulness programs can help military patients recover better after knee surgery and reduce their need for pain medication.

  Recruiting University of Utah · Fort Sam Houston, Texas · NCT05050409

• Comparison of two knee implant designs for total knee replacement

  This study is testing which of two different knee implant designs helps people who have knee replacement surgery feel better and be more satisfied afterward.

  Recruiting LifeBridge Health · Baltimore, Maryland · NCT04814082

Related topics

Quick answers

How many Knee Pain Chronic clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (7 trials), Canada (2 trials), Hong Kong (2 trials), France (1 trial), Turkey (Türkiye) (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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