Effect of Genicular Nerve Block on Recovery After Knee Surgery
Official title: The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty
Run by Pamukkale University · NCT06239649 · Data updated 2026-11-12
This study is testing if a special pain-blocking treatment before knee surgery can help patients recover faster and feel better afterward.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 40 Years to 85 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Pamukkale University Academic / other |
| Locations | 1 site (Denizli, Pamukkale) |
| Status | Recruiting |
| Started | October 19, 2023 |
| Main results expected | May 30, 2024 |
| Study ends | June 1, 2025 |
| Registry record updated | June 4, 2025 |
| Trial ID | NCT06239649 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 40 to 85 who are undergoing unilateral total knee arthroplasty due to primary knee osteoarthritis.
✕Probably not a fit
Patients with significant comorbidities, previous psychiatric disorders, or those undergoing revision knee surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effectiveness of preoperative radiofrequency genicular nerve ablation in patients undergoing total knee arthroplasty using a Fast-Track protocol. The focus is on assessing postoperative pain management, functional recovery, and early discharge criteria. By reducing pain through this non-surgical intervention, the study aims to enhance patient satisfaction and mobilization after surgery. The approach is based on previous findings that suggest genicular nerve neurolysis can significantly alleviate pain and improve quality of life for patients with knee osteoarthritis.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and faster recovery for patients undergoing knee surgery.
How similar studies have gone: Previous studies have shown that genicular nerve radiofrequency ablation is effective in reducing pain and improving function in similar patient populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being between the ages of 40 and 85, * Being able to understand verbal and written information given in Turkish, * Being able to speak and understand Turkish, * Being subjected to unilateral TKA surgery due to the diagnosis of Primary Knee osteoarthritis Exclusion Criteria: * Patients planned for revision knee prosthesis surgery, * Patients previously diagnosed with psychiatric disorders, * Patients who have undergone major surgery on the extremity where TKA will be applied, * Patients with comorbid diseases such as rheumatoid arthritis or cancer, * Patients with a score above 3 according to the American Society of Anesthesiologists (ASA) scoring, * Patients with neurological diseases that cause functional disability, * Patients with flexion limitation of more than 45 degrees and extension limitation of more than 20 degrees, * Patients who have to use hypnotic or anxiolytic drugs regularly, * Patients with alcohol or drug addiction, * Patients with bleeding disorders * Patients with uncontrolled diabetes
Where it's running
-
Pamukkale University
Denizli, Pamukkale, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Harun R Gungor, Md
- Email: hrgungor@gmail.com
- Phone: 258-296-5690
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.