Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Mindfulness interventions for military patients after knee surgery

Official title: SMART Embedded Intervention for Military Postsurgical Engagement Readiness

Run by University of Utah · NCT05050409 · Data updated 2026-11-12

This study tests if mindfulness programs can help military patients recover better after knee surgery and reduce their need for pain medication.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorUniversity of Utah
Academic / other
Locations1 site (Fort Sam Houston, Texas)
StatusRecruiting
StartedMay 1, 2022
Main results expectedJuly 2027
Study endsOctober 2027
Registry record updatedMarch 27, 2025
Trial IDNCT05050409 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are military personnel scheduled for unilateral total knee arthroplasty who are TRICARE beneficiaries.

Probably not a fit

Patients with cognitive impairments, recent contralateral knee surgeries, or current cancer diagnoses may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to optimize the use of mindfulness-based interventions for military patients undergoing total knee arthroplasty (TKA). It will evaluate the effectiveness of a brief preoperative mindfulness session and an intensive 8-week mindfulness program in improving postoperative musculoskeletal health and reducing chronic opioid use. The study will also identify patient characteristics that influence the effectiveness of these interventions. Conducted across multiple Military Health System sites, it seeks to enhance recovery outcomes for TKA patients.

Why it matters

Potential benefit: If successful, this study could significantly improve recovery and reduce opioid dependence for military patients after knee surgery.

How similar studies have gone: Other studies have shown promise in using mindfulness interventions for pain management, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Scheduled to undergo unilateral total TKA at one of the study sites
* TRICARE beneficiary
* Facility with the English language that is adequate to complete study procedures.

Exclusion Criteria:

* Cognitive impairment preventing completion of study procedures,
* Formal mindfulness training (e.g., MBSR, MBCT)
* Severe, active suicidality
* Contralateral TKA in the past 3 months or planned contralateral TKA during the study
* Current cancer diagnoses.

Where it's running

  • Brooke Army Medical Center
    Fort Sam Houston, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.